Luliconazole is an azole antifungal drug. As a 1% topical cream, luliconazole is indicated for the treatment of athlete's foot, jock itch, and ringworm caused by Trichophyton rubrum and Epidermophyton floccosum. Luliconazole is an antifungal that belongs to the azole class. Although the exact mechanism of action against dermatophytes is unknown, luliconazole appears to inhibit ergosterol synthesis by inhibiting the enzyme lanosterol demethylase. Inhibition of this enzyme's activity by azoles results in decreased amounts of ergosterol, a constituent of fungal cell membranes, and a corresponding accumulation of lanosterol. (copies from http://www.rxlist.com/luzu-drug/clinical-pharmacology.htm).
仅供研究使用。 我们不向患者出售。
化学信息
名称 | Luliconazole |
Iupac 化学名称 | Luliconazole |
同义词 | NND502; NND 502; NND502; PR2699; PR 2699; PR2699; Luzu; Lulicon |
英文同义词 | NND502; NND 502; NND502; PR2699; PR 2699; PR2699; Luzu; Lulicon |
分子式 | C14H9Cl2N3S2 |
分子量 | 354.28 |
Smile | c1cc(c(cc1Cl)Cl)[C@@H]2CS/C(=C(/C#N)\n3ccnc3)/S2 |
InChiKey | YTAOBBFIOAEMLL-REQDGWNSSA-N |
InChi | InChI=1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1 |
Cas号 | 187164-19-8 |
MDL | MFCD00953915 |
相关CAS号 | |
外观性状 | crystalline solid |
纯度 | 98% |
存储 | 3 years -20ºCpowder |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
海关编码 | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |