NVP-AUY922 is an experimental drug candidate for the treatment of cancer. It was discovered through a collaboration between The Institute of Cancer Research and the pharmaceutical company Vernalis and licensed to Novartis. It is currently in Phase II clinical trials. NVP-AUY922 is an inhibitor of heat shock protein 90 (Hsp90), which is a chaperone protein that plays a role in the modification of a variety of proteins that have been implicated in oncogenesis. NVP-AUY922 has shown promising activity in preclinical testing against several different tumor types.
Luminespib ( NVP-AUY922 ; VER-52296 ) , Bulk in stock, contact us by email for the Bulk quotation.
仅供研究使用。 我们不向患者出售。
名称 | Luminespib ( NVP-AUY922 ; VER-52296 ) |
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Iupac 化学名称 | 5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide |
同义词 | Luminespib ; NVP-AUY922 ; VER-52296 |
英文同义词 | Luminespib ; NVP-AUY922 ; VER-52296 |
分子式 | C26H31N3O5 |
分子量 | 465.54 |
Smile | OC1=C(C=C(C(=C1)O)C(C)C)C1=C(C(=NO1)C(=O)NCC)C1=CC=C(C=C1)CN1CCOCC1 |
InChiKey | NDAZATDQFDPQBD-UHFFFAOYSA-N |
InChi | InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,30-31H,4,9-12,15H2,1-3H3,(H,27,32) |
Cas号 | 747412-49-3 |
相关CAS号 | 747412-49-3 |
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