M2I-1, also known as Mad2 Inhibitor-1, is Protein-Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint. M2I-1 disturbs conformational dynamics of Mad2 critical for complex formation with Cdc20. Cellular studies revealed that M2I-1 weakens the SAC response, indicating that the compound might be active in cells.
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化学信息
名称 | M2I-1 |
Iupac 化学名称 | M2I-1 |
同义词 | M2I1; M2I 1. Mad2 Inhibitor-1 |
英文同义词 | M2I1; M2I 1. Mad2 Inhibitor-1 |
分子式 | C19H24N4O4S |
分子量 | 404.485 |
InChiKey | |
InChi | |
Cas号 | 312271-03-7 |
相关CAS号 | |
外观性状 | crystalline solid |
纯度 | 98% |
存储 | 3 years -20ºCpowder |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
海关编码 | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |