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Miltefosine

编号: 161009023
Cas号: 58066-85-6
纯度: 98% by HPLC 

Miltefosine targets cellular membranes, modulating cell membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti-apoptotic mitogen-activated protein kinase (MAPK) pathway and modulates the balance between the MAPK and pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. As an immunomodulator, miltefosine stimulates T-cells, macrophages and the expression of interleukin 3 (IL-3), granulocyte-macrophage colony stimulating factor (GM-CSF), and interferon gamma (INF-gamma). Check for active clinical trials or closed clinical trials using this agent. 

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化学信息

名称Miltefosine
Iupac 化学名称hexadecyl (2-(trimethylammonio)ethyl) phosphate 
同义词iltefosin CHePCHexadecylphosphocholineHDPCHexadecylphosphorylcholineMiltefosinum; mpavido; Miltex; Choline Phosphate Hexadecyl Ester Hydroxide Inner Salt; hexadecylphosphocholine; Miltefosin; Miltefosina; Miltefosinum; Foreign brand name: Miltex ; Abbreviation: HDPC Code name: D18506; 
英文同义词iltefosin CHePCHexadecylphosphocholineHDPCHexadecylphosphorylcholineMiltefosinum; mpavido; Miltex; Choline Phosphate Hexadecyl Ester Hydroxide Inner Salt; hexadecylphosphocholine; Miltefosin; Miltefosina; Miltefosinum; Foreign brand name: Miltex ; Abbreviation: HDPC Code name: D18506; 
分子式C21H46NO4P 
分子量407.57 
SmileP(=O)(OCCCCCCCCCCCCCCCC)(OCC[N+](C)(C)C)[O-]
InChiKeyPQLXHQMOHUQAKB-UHFFFAOYSA-N
InChiInChI=1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3
Cas号58066-85-6
相关CAS号

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外观性状Solid powder 
纯度98% by HPLC 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature 
海关编码
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Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

161009023 - Miltefosine | CAS 58066-85-6

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