Mivebresib
编号: 16123052
Cas号: 1445993-26-9
纯度: 98%
Mivebresib, also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-containing proteind) with potential antineoplastic activity. Upon administration, the bromodomain inhibitor ABBV-075 binds to the acetyl-lysine binding site in the BRD of certain BRD-containing protein(s), thereby preventing the interaction between those proteins and acetylated histones. This disrupts chromatin remodeling, prevents the expression of certain growth-promoting genes, and leads to an inhibition of cell growth in susceptible tumors.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Mivebresib |
|---|---|
| Iupac 化学名称 | N-(4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide |
| 同义词 | ABBV-075; ABBV 075; ABBV075 |
| 英文同义词 | ABBV-075; ABBV 075; ABBV075 |
| 分子式 | C22H19F2N3O4S |
| 分子量 | 459.4678 |
| Smile | FC1=C(OC2=C(C=C(C=C2)NS(=O)(=O)CC)C=2C3=C(C(N(C2)C)=O)NC=C3)C=CC(=C1)F |
| InChiKey | RDONXGFGWSSFMY-UHFFFAOYSA-N |
| InChi | InChI=1S/C22H19F2N3O4S/c1-3-32(29,30)26-14-5-7-19(31-20-6-4-13(23)10-18(20)24)16(11-14)17-12-27(2)22(28)21-15(17)8-9-25-21/h4-12,25-26H,3H2,1-2H3 |
| Cas号 | 1445993-26-9 |
| 相关CAS号 |
订购信息
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