Mizoribine,Mizoribine (INN, trade name Bredinin) is an immunosuppressive drug. The compound was first observed in Tokyo, Japan, in 1971. It is a natural product, first isolated from the mould Eupenicillium brefeldianum. Mizoribine (MZB) is an imidazole nucleoside that has been used in renal transplantation, and in steroid-resistant nephrotic syndrome, IgA nephropathy, lupus, as well as for adults with rheumatoid arthritis, lupus nephritis and other rheumatic diseases.
仅供研究使用。 我们不向患者出售。
化学信息
名称 | Mizoribine |
Iupac 化学名称 | Mizoribine |
同义词 | Bredinin; HE 69; He69; He-69; NSC289637; NSC-289637; NSC 289637; Bredinin |
英文同义词 | Bredinin; HE 69; He69; He-69; NSC289637; NSC-289637; NSC 289637; Bredinin |
分子式 | C9H13N3O6 |
分子量 | 259.22 |
Smile | c1nc(c(n1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)O)C(=O)N |
InChiKey | HZQDCMWJEBCWBR-UUOKFMHZSA-N |
InChi | InChI=1S/C9H13N3O6/c10-7(16)4-8(17)12(2-11-4)9-6(15)5(14)3(1-13)18-9/h2-3,5-6,9,13-15,17H,1H2,(H2,10,16)/t3-,5-,6-,9-/m1/s1 |
Cas号 | 50924-49-7 |
MDL | MFCD00057221 |
相关CAS号 | |
外观性状 | crystalline solid |
纯度 | 98% |
存储 | 3 years -20ºCpowder |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
海关编码 | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |