NT157 is a small-molecule tyrphostin targeting human IRSes.
仅供研究使用。 我们不向患者出售。
名称 | NT-157 |
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Iupac 化学名称 | (E)-3-(3-bromo-4,5-dihydroxyphenyl)-N-(3,4,5-trihydroxybenzyl)prop-2-enethioamide |
同义词 | NT157 ; NT 157 |
英文同义词 | NT157 ; NT 157 |
分子式 | C16H14BrNO5S |
分子量 | 412.26 |
Smile | S=C(NCC1=CC(O)=C(O)C(O)=C1)/C=C/C2=CC(O)=C(O)C(Br)=C2 |
InChiKey | NIPUPOUEGOSAAO-OWOJBTEDSA-N |
InChi | InChI=1S/C16H14BrNO5S/c17-10-3-8(4-11(19)15(10)22)1-2-14(24)18-7-9-5-12(20)16(23)13(21)6-9/h1-6,19-23H,7H2,(H,18,24)/b2-1+ |
Cas号 | 1384426-12-3 |
相关CAS号 |
包装 | 价格 | 库存 | 纯度 | 备货期 |
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大货 | 询价 | 询价 | 询价 |
外观性状 | yellow solid |
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纯度 | 98% |
存储 | 3 years -20ºCpowder |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature |
海关编码 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |
References:
1. Krueckl SL et al. Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model. Cancer Res. 2004;64:8620.
2. Gleave M, Cox M, Wang YZ: Cell biology of prostate cancer and molecular targets. In Drug Management of Prostate Cancer. (Figg, Chau, Small, Eric, Eds.) Humana Press, Springer New York Dordrecht Heidelberg London, 2010.
3. Reuveni H et al. Therapeutic Destruction of Insulin Receptor Substrates for Cancer Treatment. Cancer Res 2013;73:4383.