ONC206
编号: 111891
Cas号: 1638178-87-6
纯度: 98% Min.
ONC206 is a chemical analogue of ONC201. ONC206 is a benzyl-flurobenzyl imipridone that has highly potent activity in preclinical models of difficult-to-treat neuroendocrine tumors and sarcomas. ONC206 acts as a selective antagonist of DRD2 at nanomolar concentrations and has broad-spectrum anti-tumor activity. ONC206 may address tumor types where the properties of ONC201 do not permit for complete therapeutic engagement in vivo.
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化学信息
| 名称 | ONC206 |
|---|---|
| Iupac 化学名称 | 7-benzyl-4-(2,4-difluorobenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one |
| 同义词 | ONC206; ONC-206; ONC 206. |
| 英文同义词 | ONC206; ONC-206; ONC 206. |
| 分子式 | C23H22F2N4O |
| 分子量 | 408.4 |
| Smile | FC1=CC(F)=CC=C1CN2C(C(C3)=C(N4CCN=C42)CCN3CC5=CC=CC=C5)=O |
| InChiKey | ITMGVSSHWMTJRR-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H22F2N4O/c24-18-7-6-17(20(25)12-18)14-29-22(30)19-15-27(13-16-4-2-1-3-5-16)10-8-21(19)28-11-9-26-23(28)29/h1-7,12H,8-11,13-15H2 |
| Cas号 | 1638178-87-6 |
| 相关CAS号 |
订购信息
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