Omecamtiv mecarbil is a novel, small-molecule, direct activator of cardiac myosin, the motor protein that causes cardiac contraction. It is being evaluated as a potential treatment of heart failure in both intravenous and oral formulations with application across the continuum of care for heart failure patients from in-hospital to outpatient settings.
仅供研究使用。 我们不向患者出售。
化学信息
名称 | Omecamtiv mecarbil (CK-1827452) |
Iupac 化学名称 | methyl 4-(2-fluoro-3-(3-(6-methylpyridin-3-yl)ureido)benzyl)piperazine-1-carboxylate |
同义词 | CK 1827452; CK1827452 |
英文同义词 | CK 1827452; CK1827452 |
分子式 | C20H24FN5O3 |
分子量 | 401.43 |
Smile | O=C(N1CCN(CC2=CC=CC(NC(NC3=CC=C(C)N=C3)=O)=C2F)CC1)OC |
InChiKey | RFUBTTPMWSKEIW-UHFFFAOYSA-N |
InChi | InChI=1S/C20H24FN5O3/c1-14-6-7-16(12-22-14)23-19(27)24-17-5-3-4-15(18(17)21)13-25-8-10-26(11-9-25)20(28)29-2/h3-7,12H,8-11,13H2,1-2H3,(H2,23,24,27) |
Cas号 | 873697-71-3 |
相关CAS号 | |
外观性状 | Solid powder |
纯度 | 98% |
存储 | -20 ºC for 3 years |
可溶性 | Soluble in DMSO, Ethanol, and Water |
处理方式 | |
运输条件 | Shipped under ambient temperature |
海关编码 | |
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Mechanism | |
Cell study | |
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Clinical study | |