PI-103
编号: 160926002
Cas号: 371935-74-9
纯度: 97% by HPLC
It inhibits ATR and ATM only at much higher concentrations (IC50 = 850 and 920 nM, respectively) and exhibits little activity towards a panel of more than 40 other kinases even at concentrations as high as 10 M. Shown to effectively block PI3-K/Akt signaling and cell proliferation in glioma cell lines both in vitro and in vivo. A 10 mM (2 mg/574 l) solution of PI-103 in DMSO is also available.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | PI-103 |
|---|---|
| Iupac 化学名称 | 3-(4-(4-Morpholinyl)pyrido[3ʹ,2ʹ:4,5]furo[3,2-d]pyrimidin-2-yl)phenol |
| 同义词 | 3-(4-(4-Morpholinyl)pyrido[3ʹ,2ʹ:4,5]furo[3,2-d]pyrimidin-2-yl)phenol, mTOR Inhibitor V, PI 3-K Inhibitor V |
| 英文同义词 | 3-(4-(4-Morpholinyl)pyrido[3ʹ,2ʹ:4,5]furo[3,2-d]pyrimidin-2-yl)phenol, mTOR Inhibitor V, PI 3-K Inhibitor V |
| 分子式 | C19H16N4O3 |
| 分子量 | 348.4 |
| Smile | N1(CCOCC1)C=1C2=C(N=C(N1)C=1C=C(C=CC1)O)C1=C(O2)N=CC=C1 |
| InChiKey | TUVCWJQQGGETHL-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H16N4O3/c24-13-4-1-3-12(11-13)17-21-15-14-5-2-6-20-19(14)26-16(15)18(22-17)23-7-9-25-10-8-23/h1-6,11,24H,7-10H2 |
| Cas号 | 371935-74-9 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
