PI4KIIIbeta-IN-10
编号: 611907
Cas号: 1881233-39-1
纯度: 98%
PI4KIIIbeta-IN-10 is the most potent PI4KIII inhibitor currently reported, with very minor off-target inhibition of PI4KIII related lipid kinases (IC50 = 3.6 nM).
PI4KIIIbeta-IN-10 shows weak inhibition of PI3KC2 (IC50 1 M), PI3K (10 M), and PI4KIII (3 M), and <20% inhibition at concentrations up to 20 M for PI4K2, PI4K2, and PI3K. PI4KIIIbeta-IN-10 is also the most effective antiviral compound in a cellular model of hepatitis C virus replication, with the best balance of antiviral potency and low cellular toxicity.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | PI4KIIIbeta-IN-10 |
|---|---|
| Iupac 化学名称 | PI4KIIIbeta-IN-10 |
| 同义词 | N-(5-(3-(N-(4-hydroxyphenyl)sulfamoyl)-4-methoxyphenyl)-4-methylthiazol-2-yl)pivalamide |
| 英文同义词 | N-(5-(3-(N-(4-hydroxyphenyl)sulfamoyl)-4-methoxyphenyl)-4-methylthiazol-2-yl)pivalamide |
| 分子式 | C22H25N3O5S2 |
| 分子量 | 475.58 |
| InChiKey | |
| InChi | |
| Cas号 | 1881233-39-1 |
| 相关CAS号 |
订购信息
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