PI4KIII-IN-9 is a potent PI4KIII inhibitor (IC50 of 7 nM) and is >140-fold selective over PI3K and >20-fold selective over PI3K, and shows no inhibition of vps34 at concentrations up to 20 M.
PI4KIII-IN-9 shows weak inhibition of PI3KC2 (IC50-1 M), PI3K (2 M), and PI4KIII (2.6 M) and<50% inhibition at concentrations up to 20 M for PI4K2, PI4K2, and PI3K.
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名称 | PI4KIIIbeta-IN-9 |
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Iupac 化学名称 | PI4KIIIbeta-IN-9 |
分子式 | C23H25N3O5S2 |
分子量 | 487.59 |
InChiKey | |
InChi | |
Cas号 | 1429624-84-9 |
相关CAS号 |
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