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PIK-294

编号: 160926013
Cas号: 900185-02-6
纯度: 98% by HPLC 

PIK-294 is a highly selective inihibitor of the phosphoinositide 3-kinase (PI3K) p110 with an IC50 value of 10 nM compared to IC50 values of 10 M, 490 nM and 160 nM for PI3K//, respectively. PIK-294 has been used to help distinguish the unique roles of the various PI3-K isoforms. PIK-294 inhibited both chemokinetic and chemotactic CXCL8-induced migration. 

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化学信息

名称PIK-294
Iupac 化学名称2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one 
同义词PIK294; PIK 294; PIK-294. 
英文同义词PIK294; PIK 294; PIK-294. 
分子式C28H23N7O2 
分子量489.52792 
SmileNC1=C2C(=NC=N1)N(N=C2C2=CC(=CC=C2)O)CC2=NC1=CC=CC(=C1C(N2C2=C(C=CC=C2)C)=O)C
InChiKeyWFSLJOPRIJSOJR-UHFFFAOYSA-N
InChiInChI=1S/C28H23N7O2/c1-16-7-3-4-12-21(16)35-22(32-20-11-5-8-17(2)23(20)28(35)37)14-34-27-24(26(29)30-15-31-27)25(33-34)18-9-6-10-19(36)13-18/h3-13,15,36H,14H2,1-2H3,(H2,29,30,31)
Cas号900185-02-6
相关CAS号

订购信息

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外观性状Solid powder 
纯度98% by HPLC 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature 
海关编码
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Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

160926013 - PIK-294 | CAS 900185-02-6

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