PQR620
编号: 611821
Cas号: 1927857-56-4
纯度: 98%
PRQ620 is a highly potent and selective mTORC1/2 inhibitor, shows anti-tumor effects in vitro and in vivo.
PQR620 demonstrated its potency to prevent cancer cell growth in an NTRC 44 cancer cell line panel, resulting in a 10log(IC50) of 2.86 (nM), induced a >1000-fold selectivity towards mTOR over PI3K in enzymatic binding assays. showed excellent selectivity over a wide panel of kinases, as well as excellent selectivity versus unrelated receptor enzymes and ion channels.PQR620 result in good oral bioavailability and excellent brain penetration.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | PQR620 |
|---|---|
| Iupac 化学名称 | PQR620 |
| 同义词 | PQR-620; PQR 620 |
| 英文同义词 | PQR-620; PQR 620 |
| 分子式 | C21H25F2N7O2 |
| 分子量 | 445.47 |
| Smile | C[Si](C)(C)CSCCl |
| InChiKey | IKWIERSJEROYFH-UHFFFAOYSA-N |
| InChi | InChI=1S/C5H13ClSSi/c1-8(2,3)5-7-4-6/h4-5H2,1-3H3 |
| Cas号 | 1927857-56-4 |
| MDL | MFCD17013410 |
| 相关CAS号 |
订购信息
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| 大货 | 询价 | 询价 | 询价 |
