Peficitinib (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.ASP015K suppresses the IL-2-induced proliferation of human T cells with greater potency than EPO-induced proliferation of human erythroleukemia cells. In human whole blood, ASP015K inhibits STAT5 phosphorylation (pSTAT5).
仅供研究使用。 我们不向患者出售。
化学信息
名称 | Peficitinib (ASP015K, JNJ-54781532) |
Iupac 化学名称 | Peficitinib (ASP015K, JNJ-54781532) |
同义词 | N/A |
英文同义词 | N/A |
分子式 | C18H22N4O2 |
分子量 | 326.3 |
InChiKey | |
InChi | |
Cas号 | 944118-01-8 |
相关CAS号 | |
外观性状 | crystalline solid |
纯度 | 98% |
存储 | 3 years -20ºCpowder |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
海关编码 | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |