Phylloflavan
Phylloflavan is an antileishmanial agent with an intracellular EC50 of 3.2 nM in RAW 264.7 cells. Phylloflavan also inhibits the cytopathic effect of encephalomyocarditis virus on L929 fibroblast cells (38 U/mL).
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Phylloflavan |
|---|---|
| Iupac 化学名称 | (2R,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-3-yl (S)-5-(3,4-dihydroxyphenyl)-3-hydroxypentanoate |
| 同义词 | Phylloflavan; 9T7A4KA6YL; UNII-9T7A4KA6YL |
| 英文同义词 | Phylloflavan; 9T7A4KA6YL; UNII-9T7A4KA6YL |
| 分子式 | C26H26O10 |
| 分子量 | 498.48 |
| Smile | O=C(C[C@@H](O)CCC1=CC(O)=C(O)C=C1)O[C@H]2CC3=C(O)C=C(O)C=C3O[C@@H]2C4=CC(O)=C(O)C=C4 |
| InChiKey | FKDRTLFRRHQTGU-TYFWRAIDSA-N |
| InChi | InChI=1S/C26H26O10/c27-15(4-1-13-2-5-18(29)21(32)7-13)11-25(34)35-24-12-17-20(31)9-16(28)10-23(17)36-26(24)14-3-6-19(30)22(33)8-14/h2-3,5-10,15,24,26-33H,1,4,11-12H2/t15-,24-,26+/m0/s1 |
| Cas号 | 98570-83-3 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | 类白色固体 |
|---|---|
| 纯度 | 98% Min. |
| 存储 | 0-4℃，可保存几天到几周；-20℃，可保存 几个月。 |
| 可溶性 | 溶于DMSO等有机溶剂 |
| 处理方式 | |
| 运输条件 | 可以在室温下进行运输。 |
| 海关编码 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1: Aloufi BH, Snoussi M, Sulieman AME. Antiviral Efficacy of Selected Natural
Phytochemicals against SARS-CoV-2 Spike Glycoprotein Using Structure-Based Drug
Designing. Molecules. 2022 Apr 8;27(8):2401. doi: 10.3390/molecules27082401.
PMID: 35458599; PMCID: PMC9025634.
2: Kolodziej H, Kayser O, Kiderlen AF, Ito H, Hatano T, Yoshida T, Foo LY.
Proanthocyanidins and related compounds: antileishmanial activity and modulatory
effects on nitric oxide and tumor necrosis factor-alpha-release in the murine
macrophage-like cell line RAW 264.7. Biol Pharm Bull. 2001 Sep;24(9):1016-21.
doi: 10.1248/bpb.24.1016. PMID: 11558561.
