Pirfenidone(AMR69) is an inhibitor for TGF- production and TGF- stimulated collagen production, reduces production of TNF- and IL-1, and also has anti-fibrotic and anti-inflammatory properties. Phase 3.
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化学信息
名称 | Pirfenidone |
分子式 | C12H11NO |
分子量 | 185.22 |
Smile | Cc1ccc(=O)n(c1)c2ccccc2 |
InChiKey | ISWRGOKTTBVCFA-UHFFFAOYSA-N |
InChi | InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3 |
Cas号 | 53179-13-8 |
MDL | MFCD00866047 |
相关CAS号 | |
纯度 | 98% |
可溶性 | DMSO 37 mg/mL; Water <1 mg/mL |
处理方式 | |
海关编码 | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |