Q-VD-OPH
编号: 16071010
Cas号: 1135695-98-5
纯度: 98% by HPLC
Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm), caspase-1 (IC50=50nM), caspase-8 (IC50=100nM) and caspase-9 (IC50=430nM). It protects neurotoxin-insulted neurons from apoptotic death, as well as displays minimal toxicity. In order to reduce hydrophobicity of the peptide and to facilitate the use in aqueous media the aspartyl residue of the inhibitor is not o-methylated.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Q-VD-OPH |
|---|---|
| Iupac 化学名称 | (3S)-5-(2,6-Difluorophenoxy)-3-[[(2S)-3-Methyl-1-oxo-2-[(2-quinolinylcarbonyl)aMino]butyl]aMino]-4-oxo-pentanoic Acid |
| 同义词 | Q-VD-OPH |
| 英文同义词 | Q-VD-OPH |
| 分子式 | C26H25F2N3O6 |
| 分子量 | 513.8 |
| Smile | FC1=C(OCC([C@H](CC(=O)O)NC([C@H](C(C)C)NC(=O)C2=NC3=CC=CC=C3C=C2)=O)=O)C(=CC=C1)F |
| InChiKey | OOBJCYKITXPCNS-REWPJTCUSA-N |
| InChi | InChI=1S/C26H25F2N3O6/c1-14(2)23(31-25(35)19-11-10-15-6-3-4-9-18(15)29-19)26(36)30-20(12-22(33)34)21(32)13-37-24-16(27)7-5-8-17(24)28/h3-11,14,20,23H,12-13H2,1-2H3,(H,30,36)(H,31,35)(H,33,34)/t20-,23-/m0/s1 |
| Cas号 | 1135695-98-5 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
