Rilpivirine is a pharmaceutical drug, developed by Tibotec, for the treatment of HIV infection. It is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
仅供研究使用。 我们不向患者出售。
化学信息
名称 | Rilpivirine |
Iupac 化学名称 | 4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile |
同义词 | TMC278; TMC-278; TMC 278; Edurant |
英文同义词 | TMC278; TMC-278; TMC 278; Edurant |
分子式 | C22H18N6 |
分子量 | 366.419 |
Smile | CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)C=CC#N |
InChiKey | YIBOMRUWOWDFLG-UHFFFAOYSA-N |
InChi | InChI=1S/C22H18N6/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19/h3-9,11-13H,1-2H3,(H2,25,26,27,28) |
Cas号 | 500287-72-9 |
相关CAS号 | |
外观性状 | Solid powder |
纯度 | 98% |
存储 | -20 ºC for 3 years |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature |
海关编码 | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |