STA-21
编号: 16122706
Cas号: 111540-00-2
纯度: 98%
STA-21 is a selective STAT3 inhibitor.In cells, STA-21 inhibits Stat3 DNA binding activity, Stat3 dimerization, and Stat3-dependent luciferase activity. STA-21 remarkably inhibits the growth and the survival of the breast carcinoma cells MDA-MB-231, MDA-MB-435s, and MDA-MB-468 that express persistently activated Stat3. [1] In RH30 and RD2 cells, STA-21 also inhibits cell viability and growth and induced apoptosis through caspases 3, 8 and 9 pathways.
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化学信息
| 名称 | STA-21 |
|---|---|
| Iupac 化学名称 | STA-21 |
| 同义词 | N/A |
| 英文同义词 | N/A |
| 分子式 | C19H14O4 |
| 分子量 | 306.31 |
| Smile | C[C@H]1Cc2ccc3c(c2C(=O)C1)C(=O)c4cccc(c4C3=O)O |
| InChiKey | ZAWXOCUFQSQDJS-VIFPVBQESA-N |
| InChi | InChI=1S/C19H14O4/c1-9-7-10-5-6-12-17(15(10)14(21)8-9)19(23)11-3-2-4-13(20)16(11)18(12)22/h2-6,9,20H,7-8H2,1H3/t9-/m0/s1 |
| Cas号 | 111540-00-2 |
| MDL | MFCD09802288 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
