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Saruparib

Catalog No: 24100
CAS Number: 2589531-76-8
Purity: 98% Min.

Saruparib, also known as AZD5305 is a potent, selective and oral active PARP inhibitor. AZD5305 is a highly potent inhibitor of PARP1, with significant PARP1-DNA trapping activity, no PARP2-activity, nor binding activity to any other members of the PARP family. AZD5305 has excellent secondary pharmacology and physicochemical properties as well as high oral bioavailability in preclinical species.

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Chemical Information

NameSaruparib
Iupac Chemical Name5-(4-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)piperazin-1-yl)-N-methylpicolinamide
SynonymsAZD5305; AZD-5305; AZD 5305; Saruparib
英文同义词AZD5305; AZD-5305; AZD 5305; Saruparib
Molecular FormulaC22H26N6O2
Molecular Weight406.48
SmileO=C(C1=NC=C(N2CCN(CC3=CC(N4)=C(N=C3)C=C(CC)C4=O)CC2)C=C1)NC
InChiKeyWQAVGRAETZEADU-UHFFFAOYSA-N
InChiInChI=1S/C22H26N6O2/c1-3-16-11-19-20(26-21(16)29)10-15(12-24-19)14-27-6-8-28(9-7-27)17-4-5-18(25-13-17)22(30)23-2/h4-5,10-13H,3,6-9,14H2,1-2H3,(H,23,30)(H,26,29)
CAS Number2589531-76-8
相关CAS号

Ordering Information

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外观性状类白色固体
Purity98% Min.
Storage 0-4℃,可保存几天到几周;-20℃,可保存 几个月。
Solubility溶于DMSO等有机溶剂
处理方式
Shipping Condition可以在室温下进行运输。
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

24100 - Saruparib | CAS 2589531-76-8

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