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Serlopitant(VPD-737)

编号: 16082501
Cas号: 860642-69-9
纯度: 98% by HPLC 

Serlopitant (VPD-737) is a drug which acts as an NK1 receptor antagonist. It was assessed in clinical trials for the treatment of urinary incontinence and overactive bladder, but while it was superior to placebo it provided no advantage over existing approved drugs, and was not approved for further development.

 

仅供研究使用。 我们不向患者出售。

化学信息

名称Serlopitant(VPD-737)
Iupac 化学名称3-((3aR,4R,5S,7aS)-5-((1R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-4-(4 fluorophenyl)octahydro-2H-isoindol-2-yl)cyclopent-2-en-1-one 
同义词VPD-737; VPD737; VPD 737; MK-0594; MK 0594; MK0594 
英文同义词VPD-737; VPD737; VPD 737; MK-0594; MK 0594; MK0594 
分子式C29H28F7NO2 
分子量555.5368 
SmileFC(C=1C=C(C=C(C1)C(F)(F)F)[C@@H](C)O[C@@H]1[C@H]([C@@H]2CN(C[C@H]2CC1)C1=CC(CC1)=O)C1=CC=C(C=C1)F)(F)F
InChiKeyFLNYCRJBCNNHRH-OIYLJQICSA-N
InChiInChI=1S/C29H28F7NO2/c1-16(19-10-20(28(31,32)33)12-21(11-19)29(34,35)36)39-26-9-4-18-14-37(23-7-8-24(38)13-23)15-25(18)27(26)17-2-5-22(30)6-3-17/h2-3,5-6,10-13,16,18,25-27H,4,7-9,14-15H2,1H3/t16-,18-,25-,26+,27+/m1/s1
Cas号860642-69-9
相关CAS号

订购信息

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外观性状Solid powder 
纯度98% by HPLC 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO, not in water 
处理方式
运输条件Shipped under ambient temperature 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16082501 - Serlopitant(VPD-737) | CAS 860642-69-9

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