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Siponimod

编号: 16071404
Cas号: 1230487-00-9
纯度: 98%

 Siponimod, also known as BAF-312, is a a potent and orally selective S1P Receptor Modulator with EC50 value of 0.39nM for S1P1 receptors and 0.98nM for S1P5 receptors, respectively. Development of sphingosine-1-phosphate receptor 1 (S1P1) modulators to dampen inflammation and its sequelae is becoming increasingly promising for treating medical conditions characterized by significant immunopathology. 

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化学信息

名称Siponimod
Iupac 化学名称(E)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid 
同义词BAF-312; BAF 312; BAF312; Siponimod
英文同义词BAF-312; BAF 312; BAF312; Siponimod
分子式C29H35F3N2O3 
分子量516.6 
SmileC1(CCCCC1)C1=C(C=C(CO\N=C(/C)\C2=CC(=C(CN3CC(C3)C(=O)O)C=C2)CC)C=C1)C(F)(F)F
InChiKeyKIHYPELVXPAIDH-HNSNBQBZSA-N
InChiInChI=1S/C29H35F3N2O3/c1-3-21-14-23(10-11-24(21)15-34-16-25(17-34)28(35)36)19(2)33-37-18-20-9-12-26(22-7-5-4-6-8-22)27(13-20)29(30,31)32/h9-14,22,25H,3-8,15-18H2,1-2H3,(H,35,36)/b33-19+
Cas号1230487-00-9
相关CAS号

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外观性状Solid powder 
纯度98%
存储-20 ºC for 3 years 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16071404 - Siponimod | CAS 1230487-00-9

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