TAK-580 (MLN2480)
编号: 16062203
Cas号: 1096708-71-2
纯度: 98% by HPLC
TAK-580, also known as MLN2480, BIIB024, and AMG 2112819, is an oral, selective pan-Raf kinase inhibitor. The Raf kinases (A-Raf, B-Raf and C-Raf) are key regulators of cell proliferation and survival within the mitogen-activated protein kinase (MAPK) pathway. The MAPK pathway is frequently disregulated in human cancers, often via activating mutations of Ras or Raf.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | TAK-580 (MLN2480) |
|---|---|
| Iupac 化学名称 | (R)-2-(1-(6-amino-5-chloropyrimidine-4-carboxamido)ethyl)-N-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide |
| 同义词 | TAK580; MLN 2480 |
| 英文同义词 | TAK580; MLN 2480 |
| 分子式 | C17H12Cl2F3N7O2S |
| 分子量 | 506.29 |
| Smile | NC1=C(C(=NC=N1)C(=O)N[C@H](C)C=1SC(=CN1)C(=O)NC1=NC=C(C(=C1)C(F)(F)F)Cl)Cl |
| InChiKey | VWMJHAFYPMOMGF-ZCFIWIBFSA-N |
| InChi | InChI=1S/C17H12Cl2F3N7O2S/c1-6(28-15(31)12-11(19)13(23)27-5-26-12)16-25-4-9(32-16)14(30)29-10-2-7(17(20,21)22)8(18)3-24-10/h2-6H,1H3,(H,28,31)(H2,23,26,27)(H,24,29,30)/t6-/m1/s1 |
| Cas号 | 1096708-71-2 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
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