TH-263
编号: 2061303
Cas号: 313520-94-4
纯度: 98% Min.
TH-263 is an inactive analog control for the type III allosteric LIM-kinase (LIMK) inhibitors TH-257, TH-255 and TH-251. LIM kinases belong to the family of cytoplasmic tyrosine-like kinases with dual specificity (serine/threonine and tyrosine). However, known LIMK substrate are usually phosphorylated at serine and threonine residues LIM kinases comprises LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2) which show 50% sequence identity in human. Both LIMK1 and LIMK2 present with a unique domain organization containing two N-terminal LIM domains, a PDZ domain, a proline/serine-rich domain and a C-terminal kinase domain.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | TH-263 |
|---|---|
| Iupac 化学名称 | N-benzyl-4-(N-benzylsulfamoyl)benzamide |
| 同义词 | TH-263; TH 263; TH263; |
| 英文同义词 | TH-263; TH 263; TH263; |
| 分子式 | C21H20N2O3S |
| 分子量 | 380.462 |
| Smile | O=C(NCC1=CC=CC=C1)C2=CC=C(S(=O)(NCC3=CC=CC=C3)=O)C=C2 |
| InChiKey | QDGVJMITKNOVTP-UHFFFAOYSA-N |
| InChi | InChI=1S/C21H20N2O3S/c24-21(22-15-17-7-3-1-4-8-17)19-11-13-20(14-12-19)27(25,26)23-16-18-9-5-2-6-10-18/h1-14,23H,15-16H2,(H,22,24) |
| Cas号 | 313520-94-4 |
| 相关CAS号 |
订购信息
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