TYRA-300
编号: 24073
Cas号: 2800223-30-5
纯度: 98% Min.
TYRA-300 is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the Treatment of Urothelial Cancers and Achondroplasia. TYRA-300 was conceived using a structure-based approach as a potent FGFR3-selective inhibitor to avoid the toxicities associated with inhibition of FGFR1, FGFR2, and FGFR4, and to be agnostic for the FGFR3 gatekeeper mutations.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | TYRA-300 |
|---|---|
| Iupac 化学名称 | (R)-5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-3-(6-(6-(methylsulfonyl)-2,6-diazaspiro[3.3]heptan-2-yl)pyridin-3-yl)-1H-indazole |
| 同义词 | TYRA-300; TYRA300; TYRA 300 |
| 英文同义词 | TYRA-300; TYRA300; TYRA 300 |
| 分子式 | C25H24Cl2N6O3S |
| 分子量 | 559.47 |
| Smile | O=S(N(C1)CC1(C2)CN2C(N=C3)=CC=C3C4=NNC5=CC=C(O[C@H](C)C6=C(Cl)C=NC=C6Cl)C=C54)(C)=O |
| InChiKey | JOAFWIHZEBKYQK-OAHLLOKOSA-N |
| InChi | InChI=1S/C25H24Cl2N6O3S/c1-15(23-19(26)9-28-10-20(23)27)36-17-4-5-21-18(7-17)24(31-30-21)16-3-6-22(29-8-16)32-11-25(12-32)13-33(14-25)37(2,34)35/h3-10,15H,11-14H2,1-2H3,(H,30,31)/t15-/m1/s1 |
| Cas号 | 2800223-30-5 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
