Tirabrutinib free base ( ONO-4059 )
编号: 17031303
Cas号: 1351636-18-4
纯度: ≧98.0%
Tirabrutinib, also known as ONO-4059 is a potent and orally active Bruton agammaglobulinemia tyrosine kinase (BTK) inhibitor. Upon administration, ONO-4059 covalently binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Tirabrutinib free base ( ONO-4059 ) |
|---|---|
| Iupac 化学名称 | (R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one |
| 同义词 | ONO-4059 ; ONO4059 ; ONO 4059 ; ONO-4059 ; GS 4059 ; GS-4059 ; GS4059 ; ONO-WG-307 ; Tirabrutinib |
| 英文同义词 | ONO-4059 ; ONO4059 ; ONO 4059 ; ONO-4059 ; GS 4059 ; GS-4059 ; GS4059 ; ONO-WG-307 ; Tirabrutinib |
| 分子式 | C25H22N6O3 |
| 分子量 | 454.49 |
| Smile | NC1=C2N(C(N(C2=NC=N1)[C@H]1CN(CC1)C(C#CC)=O)=O)C1=CC=C(C=C1)OC1=CC=CC=C1 |
| InChiKey | SEJLPXCPMNSRAM-GOSISDBHSA-N |
| InChi | InChI=1S/C25H22N6O3/c1-2-6-21(32)29-14-13-18(15-29)31-24-22(23(26)27-16-28-24)30(25(31)33)17-9-11-20(12-10-17)34-19-7-4-3-5-8-19/h3-5,7-12,16,18H,13-15H2,1H3,(H2,26,27,28)/t18-/m1/s1 |
| Cas号 | 1351636-18-4 |
| 相关CAS号 | 1351636-18-4 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | Off-white solid |
|---|---|
| 纯度 | ≧98.0% |
| 存储 | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| 可溶性 | Soluble in DMSO |
| 处理方式 | Refer to MSDS |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| 海关编码 | 2934200090 |
Coming soon.
| Targets | BTK inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
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