Triciribine
编号: 161009022
Cas号: 35943-35-2
纯度: 98% by HPLC
Triciribine inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3, which may result in the inhibition of Akt-expressing tumor cell proliferation. Akts are anti-apoptotic serine/theronine-specific protein kinases that phosphorylate and inactivate components of the apoptotic machinery, including Bcl-xL/Bcl-2-associated death promoter (BAD) and caspase 9. Check for active clinical trials or closed clinical trials using this agent.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Triciribine |
|---|---|
| Iupac 化学名称 | (2R,3R,4S,5R)-2-(3-amino-5-methyl-1,4,5,6,8-pentaazaacenaphthylen-1(5H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. |
| 同义词 | VQD002TCNPtriciribineTricyclic nucleoside; PentaazacentopthyleneAPI2Akt Inhibitor V. |
| 英文同义词 | VQD002TCNPtriciribineTricyclic nucleoside; PentaazacentopthyleneAPI2Akt Inhibitor V. |
| 分子式 | C13H16N6O4 |
| 分子量 | 320.3 |
| Smile | CN1c2c3c(cn(c3ncn2)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)C(=N1)N |
| InChiKey | HOGVTUZUJGHKPL-HTVVRFAVSA-N |
| InChi | InChI=1S/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/m1/s1 |
| Cas号 | 35943-35-2 |
| MDL | MFCD00932413 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
