UNC-2025 is a novel potent and highly orally bioavailable Mer/FLT3 dual inhibitor, capable of inhibiting Mer phosphorylation in vivo, following oral dosing as demonstrated by pharmaco-dynamic (PD) studies examining phospho-Mer in leukemic blasts from mouse bone marrow.
仅供研究使用。 我们不向患者出售。
化学信息
名称 | UNC-2025 |
Iupac 化学名称 | (1r,4r)-4-(2-(butylamino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexanol |
同义词 | UNC-2025; UNC2025; UNC 2025 |
英文同义词 | UNC-2025; UNC2025; UNC 2025 |
分子式 | C28H40N6O |
分子量 | 476.66 |
InChiKey | |
InChi | |
Cas号 | 1429881-91-3 |
相关CAS号 | |
外观性状 | White solid powder |
纯度 | 97% |
存储 | -20 ºC for 3 years |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature |
海关编码 | |
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Mechanism | |
Cell study | |
Animal study | |
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