UNC0638
编号: 82403
Cas号: 1255580-76-7
纯度: 98%
UNC0638 is an inhibitor of G9a and GLP with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets. UNC0638 treatment of a variety of cell lines resulted in lower global H3K9me2 levels, equivalent to levels observed for small hairpin RNA knockdown of G9a and GLP with the functional potency of UNC0638 being well separated from its toxicity.
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化学信息
| 名称 | UNC0638 |
|---|---|
| Iupac 化学名称 | 2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine |
| 同义词 | UNC 0638; UNC-0638 |
| 英文同义词 | UNC 0638; UNC-0638 |
| 分子式 | C30H47N5O2 |
| 分子量 | 509.73 |
| Smile | C1(CCCCC1)C1=NC2=CC(=C(C=C2C(=N1)NC1CCN(CC1)C(C)C)OC)OCCCN1CCCC1 |
| InChiKey | QOECJCJVIMVJGX-UHFFFAOYSA-N |
| InChi | InChI=1S/C30H47N5O2/c1-22(2)35-17-12-24(13-18-35)31-30-25-20-27(36-3)28(37-19-9-16-34-14-7-8-15-34)21-26(25)32-29(33-30)23-10-5-4-6-11-23/h20-24H,4-19H2,1-3H3,(H,31,32,33) |
| Cas号 | 1255580-76-7 |
| 相关CAS号 |
订购信息
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