Ulipristal acetate, also known as CDB-2914, is a selective progesterone receptor modulator (SPRM) approved for contraception, and for uterine fibroid. As a SPRM, ulipristal acetate has partial agonistic as well as antagonistic effects on the progesterone receptor. It also binds to the glucocorticoid receptor, but is only a weak antiglucocorticoid relative to mifepristone, and has no relevant affinity to the estrogen, androgen and mineralocorticoid receptors.
仅供研究使用。 我们不向患者出售。
化学信息
名称 | Ulipristal acetate |
Iupac 化学名称 | Ulipristal acetate |
同义词 | CDB-2914; CDB 2914; CDB2914; HRP-2000; HRP 2000; HRP2000; VA2914; VA-2914; VA 2914; RTI 3021-012; RU 44675; Ulipristal acetate. EllaOne; Ella. Esmya |
英文同义词 | CDB-2914; CDB 2914; CDB2914; HRP-2000; HRP 2000; HRP2000; VA2914; VA-2914; VA 2914; RTI 3021-012; RU 44675; Ulipristal acetate. EllaOne; Ella. Esmya |
分子式 | C30H37NO4 |
分子量 | 475.629 |
Smile | CC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)c5ccc(cc5)N(C)C)C)OC(=O)C |
InChiKey | OOLLAFOLCSJHRE-ZHAKMVSLSA-N |
InChi | InChI=1S/C30H37NO4/c1-18(32)30(35-19(2)33)15-14-27-25-12-8-21-16-23(34)11-13-24(21)28(25)26(17-29(27,30)3)20-6-9-22(10-7-20)31(4)5/h6-7,9-10,16,25-27H,8,11-15,17H2,1-5H3/t25-,26+,27-,29-,30-/m0/s1 |
Cas号 | 126784-99-4 |
MDL | MFCD00899035 |
相关CAS号 | |
外观性状 | crystalline solid |
纯度 | 98% |
存储 | 3 years -20ºCpowder |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
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Mechanism | |
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