Vortioxetine Hcl (Lu AA21004 Hcl) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
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化学信息
名称 | Vortioxetine hydrobromide |
分子式 | C18H23BrN2S |
分子量 | 379.36 |
Smile | Cc1ccc(c(c1)C)Sc2ccccc2N3CCNCC3.Br |
InChiKey | VNGRUFUIHGGOOM-UHFFFAOYSA-N |
InChi | InChI=1S/C18H22N2S.BrH/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20;/h3-8,13,19H,9-12H2,1-2H3;1H |
Cas号 | 960203-27-4 |
MDL | MFCD22383961 |
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纯度 | 98% |
可溶性 | DMSO 76 mg/mL; Water <1 mg/mL; Ethanol 17 mg/mL |
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