YCT529, an RAR-α inhibitor, is used as a contraceptive, with a 99% effectiveness. YCT529 acts as a potent and selective antagonist of the Vitamin A receptor retinoic acid receptor alpha (RAR-α). In studies on mice it produced a 99% reduction in sperm production, and it has proceeded to early stage human clinical trials as a potential male contraceptive.
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名称 | YCT529 |
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Iupac 化学名称 | sodium 4-(5-(2,2-dimethyl-4-(p-tolyl)-2H-chromen-6-yl)-1H-pyrrol-2-yl)benzoate |
同义词 | YCT529; YCT 529; YCT-529 |
英文同义词 | YCT529; YCT 529; YCT-529 |
分子式 | C29H24NNaO3 |
分子量 | 457.50 |
Smile | O=C([O-])C1=CC=C(C2=CC=C(C3=CC(C(C4=CC=C(C)C=C4)=CC(C)(C)O5)=C5C=C3)N2)C=C1.[Na+] |
InChiKey | NNFWFHLHNJSJTH-UHFFFAOYSA-M |
InChi | InChI=1S/C29H25NO3.Na/c1-18-4-6-19(7-5-18)24-17-29(2,3)33-27-15-12-22(16-23(24)27)26-14-13-25(30-26)20-8-10-21(11-9-20)28(31)32;/h4-17,30H,1-3H3,(H,31,32);/q;+1/p-1 |
Cas号 | 2863670-67-9 |
相关CAS号 |
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