YF-2 hydrochloride is a highly selective, blood-brain-barrier permeable histone acetyltransferase activitor, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease.
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| 名称 | YF-2 hydrochloride |
|---|---|
| 同义词 | YF-2 hydrochloride;YF-2 HCI. |
| 英文同义词 | YF-2 hydrochloride;YF-2 HCI. |
| 分子式 | C20H23Cl2F3N2O3 |
| 分子量 | 467.31 |
| Smile | O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=C(OCC)C=CC=C2OCCN(C)C.Cl |
| InChiKey | |
| InChi | |
| Cas号 | 1312005-62-1 |
| 相关CAS号 |
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | Off-white solid to white solid |
|---|---|
| 纯度 | >98% |
| 存储 | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| 可溶性 | Soluble in DMSO |
| 处理方式 | |
| 运输条件 | Shipped under ambient temperature |
| 海关编码 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |