Z-DEVD-FMK
编号: 16062112
Cas号: 210344-95-9
纯度: 98% by HPLC
Z-DEVD-FMK(Caspase-3 Inhibitor) is a specific, irreversible Caspase-3 inhibitor, and also shows potent inhibition on caspase-6, caspase-7, caspase-8, and caspase-10. IC50 value: Target: Caspase3 inhibitor in vitro: Z-DEVD-FMK (1C200 M) inhibits D4-GDI cleavage and apoptosis in a concentration-dependent manner [1]. Z-DEVD-FMK reduces ceramide-induced cardiomyocyte death and significantly inhibits the activation of caspase 3 [3]. Z-DEVD-FMK (100 M) blocks MPP+-induced increases in caspase-3 enzyme activity. Z-DEVD-FMK dose dependently blocks 6-OHDA-induced apoptotic cell death with IC50 of 18 M [4]. in vivo: Z-DEVD-FMK, before and after injury, markedly reduces post-traumatic apoptosis, and significantly improved neurological recovery
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Z-DEVD-FMK |
|---|---|
| Iupac 化学名称 | Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK |
| 同义词 | Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK |
| 英文同义词 | Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK |
| 分子式 | C30H41FN4O13 |
| 分子量 | 684.66 |
| Smile | CC(C)[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](CCC(=O)OC)NC(=O)[C@H](CC(=O)OC)NC(=O)OCc1ccccc1 |
| InChiKey | GBJVAVGBSGRRKN-JYEBCORGSA-N |
| InChi | InChI=1S/C30H41FN4O12/c1-17(2)26(29(42)33-20(22(36)15-31)13-24(38)45-4)35-27(40)19(11-12-23(37)44-3)32-28(41)21(14-25(39)46-5)34-30(43)47-16-18-9-7-6-8-10-18/h6-10,17,19-21,26H,11-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,43)(H,35,40)/t19-,20-,21-,26-/m0/s1 |
| Cas号 | 210344-95-9 |
| MDL | MFCD23380217 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
