Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibitor that covalently binds to the tyrosine kinase domain of both wild type and mutated HER2 receptors, including those with an exon 20 insertion.
仅供研究使用。 我们不向患者出售。
Name | Zongertinib |
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Iupac Chemical Name | N-[1-(8-[3-Methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]anilino]pyrimido[5,4-d]pyrimidin-2-yl)piperidin-4-yl]prop-2-enamide |
Synonyms | BI 1810631 ; BI1810631 ; BI-1810631 ; Zongertinib |
英文同义词 | BI 1810631 ; BI1810631 ; BI-1810631 ; Zongertinib |
Molecular Formula | C29H29N9O2 |
Molecular Weight | 535.61 |
Smile | C=CC(NC1CCN(C2=NC=C(N=CN=C3NC4=CC=C(OC5=CC=C6C(N=CN6C)=C5)C(C)=C4)C3=N2)CC1)=O |
InChiKey | YSGNGFPNTLERCR-UHFFFAOYSA-N |
InChi | InChI=1S/C29H29N9O2/c1-4-26(39)34-19-9-11-38(12-10-19)29-30-15-23-27(36-29)28(32-16-31-23)35-20-5-8-25(18(2)13-20)40-21-6-7-24-22(14-21)33-17-37(24)3/h4-8,13-17,19H,1,9-12H2,2-3H3,(H,34,39)(H,31,32,35) |
CAS Number | 2728667-27-2 |
相关CAS号 | 2728667-27-2 |
包装 | Price | 库存 | Purity | 备货期 |
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大货 | Enquiry | Enquiry | Enquiry |
外观性状 | Solid powder |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO |
处理方式 | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
海关编码 | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |