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b-AP15

编号: 73106
Cas号: 1009817-63-3
纯度: 97% 

b-AP15 is a specific inhibitor of the deubiquitinating enzymes Uch37 and Usp14 of the 26S proteasome. It blocks the deubiquitinating activity of the 26S proteasome. Treating cells with b-AP15 causes the accumulation of polyubiquitinated proteins, inhibition of proteasomal degradation, upregulation of apoptotic markers and cell death. 

仅供研究使用。 我们不向患者出售。

化学信息

名称b-AP15
Iupac 化学名称(3E,5E)-1-acryloyl-3,5-bis(4-nitrobenzylidene)piperidin-4-one 
同义词NSC687852; NSC 687852; NSC-687852 
英文同义词NSC687852; NSC 687852; NSC-687852 
分子式C22H17N3O6 
分子量419.39 
SmileC(C=C)(=O)N1C\C(\C(/C(/C1)=C/C1=CC=C(C=C1)[N+](=O)[O-])=O)=C/C1=CC=C(C=C1)[N+](=O)[O-]
InChiKeyGFARQYQBWJLZMW-JYFOCSDGSA-N
InChiInChI=1S/C22H17N3O6/c1-2-21(26)23-13-17(11-15-3-7-19(8-4-15)24(28)29)22(27)18(14-23)12-16-5-9-20(10-6-16)25(30)31/h2-12H,1,13-14H2/b17-11+,18-12+
Cas号1009817-63-3
相关CAS号

订购信息

包装价格库存纯度备货期
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外观性状Yellow solid powder 
纯度97% 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

73106 - b-AP15 | CAS 1009817-63-3

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