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BMS-986141

编号: 20518
Cas号: 1478711-48-6
纯度: 98% Min.

BMS-986141 is an Orally-Active Small-Molecule Antagonist of the Platelet Protease-Activated Receptor-4 (PRA4 antagonist), BMS-986141, Prevents Aeterial Thrombosis With Low Bleeding Liability in Cynomolgus Monkeys. BMS-986141 inhibited platelet aggregation induced by PAR4-AP in human and monkey blood in vitro with comparable IC50of 1.8±0.3 and 1.2±0.3 nM, respectively


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化学信息

名称BMS-986141
Iupac 化学名称4-[4-[[6-methoxy-2-(2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-1-benzofuran-4-yl]oxymethyl]-1,3-thiazol-2-yl]-N,N-dimethylbenzamide
同义词BMS-986141; BMS 986141; BMS986141;
英文同义词BMS-986141; BMS 986141; BMS986141;
分子式C27H23N5O5S2
分子量561.63
SmileO=C(N(C)C)C1=CC=C(C2=NC(COC3=CC(OC)=CC4=C3C=C(C5=CN6C(SC(OC)=N6)=N5)O4)=CS2)C=C1
InChiKeyKEEBLYWBELVGPQ-UHFFFAOYSA-N
InChiInChI=1S/C27H23N5O5S2/c1-31(2)25(33)16-7-5-15(6-8-16)24-28-17(14-38-24)13-36-21-9-18(34-3)10-22-19(21)11-23(37-22)20-12-32-26(29-20)39-27(30-32)35-4/h5-12,14H,13H2,1-4H3
Cas号1478711-48-6
相关CAS号

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包装价格库存纯度备货期
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外观性状固体粉末
纯度98% Min.
存储短期(几天到几周)为0-4摄氏度,长期(几个月)为-20摄氏度
可溶性溶于DMSO
处理方式
运输条件作为非危险化学品在环境温度下装运。这种产品在正常运输和海关工作期间可以稳定几周.
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study

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化学结构

20518 - BMS-986141 | CAS 1478711-48-6

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