重点产品
| 编号 | 化学名称 | Cas号 | 纯度 | 化学结构 |
|---|---|---|---|---|
| 92802 | SAG | 912545-86-9 | 99.03% |  |
| SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); antagonizes Cyclopami | ||||
| 102703 | AZD-8835 | 1620576-64-8 | ≧98.0% |  |
| AZD8835 is a potent and selective inhibitor ofPI3KαandPI3KδwithIC50s of 6.2 and 5.7 | ||||
| 111013 | MGCD-265-analog | 875337-44-3 | ≧98.0% |  |
| MGCD-265-analogis a tyrosine kinase inhibitor that selectively targets MET and Axl.MG | ||||
| 112101 | AV-412 | 451492-95-8 | 99.38% |  |
| AV-412 is an EGFR/HER2 inhibitor that binds to and inhibits the epidermal growth fact | ||||
| 120103 | AGI-5198 | 1355326-35-0 | 98% |  |
| AGI-5198 is a novel R132H-IDH1 inhibitor, identified through a high-throughput screen | ||||
| 122203 | Dalcetrapib | 211513-37-0 | 98% |  |
| Dalcetrapib is a rhCETP inhibitor with IC50 of 0.2 M that increases the plasma HDL ch | ||||
| 122518 | SB-742457 ( Intepirdine ) | 607742-69-8 | 98% |  |
| SB-742457(Intepirdine) is a highly selective 5-HT6 receptor antagonist with pKi of 9. | ||||
| 122524 | GW2580 | 870483-87-7 | 98% |  |
| GW2580 is an orally bioavailable inhibitor of c-FMS kinase; completely inhibited huma | ||||
| 122805 | Balipodect ( TAK-063 ) | 1238697-26-1 | 98% | _1238697-26-1.png) |
| Balipodect (TAK 063 )is a novel PDE10A inhibitor. It has shown high inhibitory activi | ||||
| 122919 | Tenapanor | 1234423-95-0 | 98% |  |
| Tenapanoris an inhibitor of the sodium-proton exchanger NHE3. Thisantiporter protein | ||||
| 122941 | Pacritinib(SB1518) | 937272-79-2 | ≧98.0% |  |
| Pacritinib (SB1518) 是一种高选择性激酶抑制剂，对 JAK2、FLT3、IRAK1 和 | ||||
| 1662118 | MK-8931 ( Verubecestat ) | 1286770-55-5 | 98% by HPLC/HNMR | -cas-1286770-55-5.png) |
| MK-8931(verubecestat)是一种BACE抑制剂，是由默沙东公司研制开发。主 | ||||