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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
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Immunology & Inflammation
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Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
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Name Index F
FLAG-003
(Catalog# : 20640, Cas# :
1614235-14-1
)
FLAG-003 is a multi-acting, water-soluable small molecule therapeutic designed to tar
FC-116
(Catalog# : 20569, Cas# :
2417298-29-2
)
FC-116 is a Tubulin inhibitor that effectively inhibits tumor growth in mice.
F7H inhibitor
(Catalog# : 20556, Cas# :
897109-93-2
)
F7H is a Frizzled receptor FZD7 antagonist.
Flavopiridol ( Alvocidib )
(Catalog# : 237071, Cas# :
146426-40-6
)
Alvocidib is a synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is subst
FHD-286
(Catalog# : 20471, Cas# :
2671128-05-3
)
FHD-286 is an oral, small-molecule, selective, allosteric inhibitor of BRG1 and BRM i
3-fluoro-6-methoxyquinoline
(Catalog# : 20433, Cas# :
426842-85-5
)
5-Fluoroquinazoline-2,4(1H,3H)-dione
(Catalog# : 20420, Cas# :
192570-33-5
)
4-Fluoro-2-(trifluoromethyl)benzaldehyde
(Catalog# : 20405, Cas# :
90176-80-0
)
Fosgonimeton (ATH-1017)
(Catalog# : 1711225, Cas# :
2093305-05-4
)
Fosgonimeton (ATH-1017) is a small molecule which enhance the activity of hepatocyte
Fadraciclib free base
(Catalog# : L20347, Cas# :
1070790-89-4
)
Fadraciclib, also known as CYC065, is an orally bioavailable inhibitor of cyclin depe
F1063-0967
(Catalog# : 20315, Cas# :
613225-56-2
)
F1063-0967 is a novel inhibitor of dual-specificity phosphatase 26 (DUSP26), inducing
1-[6-(4-fluoro-1H-pyrazol-1-yl)-3-pyridinyl]Ethanone
(Catalog# : 20262, Cas# :
1980023-94-6
)
Firibastat ( QGC-001 )
(Catalog# : 26188, Cas# :
648927-86-0
)
Firibastat, (originally named QGC001) is the first drug candidate of a new class of c
FM-381
(Catalog# : 20122201, Cas# :
2226521-65-7
)
FM-381 is a Chemical Probe For JAK3 and JAK3 specific reversible covalent inhibitor.
FOY-251 mesylate
(Catalog# : 2091911, Cas# :
71079-09-9
)
FOY-251 is a metabolite of Camostat that acts as a pollen protease inhibitor for prev
FG-7142
(Catalog# : 2091909, Cas# :
78538-74-6
)
FG-7142 is a benzodiazepine receptor ligand with anxiogenic and proconvulsant propert
FT113
(Catalog# : 2071557, Cas# :
1630808-89-7
)
FT113 is a novel potent inhibitor of fatty acid synthase (fasn)
Fulacimstat
(Catalog# : 2071514, Cas# :
1488354-15-9
)
Fulacimstat, also known as BAY1142524, is a chymase inhibitor and antifibrotic drug c
FB23-2
(Catalog# : 207102, Cas# :
2243736-45-8
)
FB23-2 is a potent FTO inhibitor. FB23-2 demonstrated the potent inhibitory impact in
2-(3-Fluoro-4-isopropoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
(Catalog# : 262324, Cas# :
1350426-06-0
)
2-fluoro-4-methyl-5-nitrobenzoic acid methyl ester
(Catalog# : 2062015, Cas# :
753924-48-0
)
FTI-2148
(Catalog# : 111897, Cas# :
251577-09-0
)
FTI-2148 is a potent farnesyltransferase inhibitor with potential antitumor activity.
FR-190809
(Catalog# : 193253, Cas# :
215589-63-2
)
FR-190809 is a potent, nonadrenotoxic, orally efficacious ACAT inhibitor.
FM19G11
(Catalog# : 192211, Cas# :
329932-55-0
)
FM19G11 is an inhibitor of Hypoxia Inducible Factors α (HIFα), reported to affect s
Fmk
(Catalog# : 188102, Cas# :
821794-92-7
)
Potent irreversible RSK1/2 inhibitor (IC50 = 15 nM). Inactivates the C-terminal auto-
Fluspirilene
(Catalog# : 18794, Cas# :
1841-19-6
)
Fluspirilene is a diphenylbutylpiperidine typical antipsychotic drug, used for the tr
Fezolinetant
(Catalog# : 18722, Cas# :
1629229-37-3
)
Fezolinetant, also known as ESN-364, is Neurokinin-3 (NK-3) receptor antagonist which
FRAX486
(Catalog# : 18721, Cas# :
1232030-35-1
)
FRAX486 is a potent p21-activated kinase (PAK) inhibitor (IC50 values are 14, 33, 39
Fialuridine
(Catalog# : 184283, Cas# :
69123-98-4
)
Fialuridine, also known as FIAU, DRG-0098, is a DNA-directed DNA polymerase inhibitor
Fonadelpar
(Catalog# : 18445, Cas# :
515138-06-4
)
Fonadelpar is a potent and selective peroxisome proliferator activated receptor δ (P
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).