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PI3K/Akt/mTOR
Epigenetics
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Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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DNA Damage
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
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GPCR & G Protein
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Cas Index 8
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Cas Index 8
899805-25-5 | Tanzisertib
(Catalog# : 011903)
Tanzisertib is a potent, selective, and orally active JNK inhibitor with potential an
871576-03-3 | TGN 255
(Catalog# : 011114)
Coming soon!
856867-55-5 | Tedizolid phosphate
(Catalog# : 120713)
Tedizolid phosphate is an oxazolidinone drug being developed by Cubist Pharmaceutical
852821-06-8 | TP808
(Catalog# : 92217)
Coming soon!
886499-50-9 | 3-(3,4,5-Trifluorophenyl)propanoic acid
(Catalog# : 90620)
Coming soon!
865759-25-7 | Trelagliptin
(Catalog# : 52725)
Trelagliptin(SYR-472) is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that
856866-72-3 | Tedizolid
(Catalog# : 52715)
Torezolid (TR-701; tedizolid) is a novel oxazolidinone for gram-positive infections.
871700-17-3 | Trametinib (GSK1120212)
(Catalog# : 52109)
Trametinib (GSK1120212) is a highly specific and potentMEK1/2inhibitor withIC50of 0.9
847239-17-2 | UVI3003
(Catalog# : 19343)
UVI3003 is a RXR antagonist. It displays high RXR binding affinity. UVI3003 does not
869113-09-7 | Umeclidinium bromide
(Catalog# : 72801)
Umeclidinium bromide is an anticholinergic drug approved for use in combination with
869853-70-3 | VAS3947
(Catalog# : 20302)
VAS3947 is a selective inhibitor of NADPH oxidase activity in low micromolar concentr
85511-68-8 | VU0238441
(Catalog# : 2071627)
890655-80-8 | Verdiperstat
(Catalog# : 1812285)
erdiperstat, also known as AZD-3241, is a selective and irreversible inhibitor of mye
845272-21-1 | Varlitinib
(Catalog# : 2017885)
ARRY334543 is a potent selective ErbB-1 and ErbB-2 inhibitor (IC50=7and 2 nM, respect
896720-20-0 | VX-11e
(Catalog# : 120806)
Coming soon!
869886-67-9 | VRT752271
(Catalog# : 92212)
Coming soon!
879085-55-9 | Vismodegib(GDC-0449)
(Catalog# : 52307)
Vismodegib (GDC-0449) is a potent, novel and specifichedgehoginhibitor withIC50of 3 n
856243-80-6 | WP-1130
(Catalog# : 11022)
Degrasyn, also known as WP1130, is a small molecule that specifically and rapidly dow
890190-22-4 | WDR5-0103
(Catalog# : 16122845)
WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 (Kd = 450 n
853220-52-7 | Wnt agonist 1
(Catalog# : 16122786)
Wnt agonist 1 is a cell permeable Wnt signaling pathway activator, which induces -cat
857064-38-1 | WP1066
(Catalog# : 122527)
WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 M and 2.43 M in HEL c
838818-26-1 | WIKI4
(Catalog# : 73102)
WIKI4 is a novel Tankyrase inhibitor with IC50 of 15 nM for TNKS2, and leads to inhib
878419-78-4 | Walrycin B
(Catalog# : 52539)
Walrycin B is a novel antibacterial compound specifically targeting the essential Wal
837422-57-8 | WH-4-023
(Catalog# : 52402)
WH-4-023 is a potent and orally activeLck/Srcinhibitor withIC50of 2 nM and 6 nM, resp
890402-73-0 | XP-59
(Catalog# : 2071549)
XP-59 is a potent inhibitor of the SARS-CoV Mpro
898280-07-4 | XL228
(Catalog# : 123011)
XL228 is a protein kinase inhibitor targeting IGF1R, the Aurora kinases, FGFR1-3, ABL
879127-07-8 | YUN27078
(Catalog# : 2071610)
YUN27078, also known as EGFR inhibitor, is an EGFR inhibitor. It directly depolymeriz
801991-87-7 | ZZW-115
(Catalog# : 20301)
ZZW-115is a potent NUPR1 inhibitor. ZZW-115 induces ferroptosis in a mitochondria-dep
874911-96-3 | ZK756326
(Catalog# : 16122725)
ZK756326 is a full agonist of CCR8Chemokine receptor 8 with an IC50 of 1.8 M, dose-re
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
1393466-87-9 | PLX8394
(Catalog# : 20613)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).