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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
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MAPK
Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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Membrane Transporter/Ion Channel
others
PROTAC
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Cas Index 1
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Cas Index 1
1616113-45-1 | VRT-1353385
(Catalog# : 101912)
Coming soon!
1257044-40-8 | Venetoclax(ABT-199)
(Catalog# : 60101)
Venetoclax, formerly known as ABT-199(GDC-0199), is a Bcl-2-selective inhibitor with
1246560-33-7 | VS-5584
(Catalog# : 52530)
VS-5584 (SB2343) is a potent and selective dual PI3K/mTOR inhibitor for mTOR, PI3K///
1232416-25-9 | VE-822 ( Berzosertib )
(Catalog# : 51607)
VE-822(Berzosertib), an analogue of VE-821 with increased potency and selectivity aga
107355-45-3 | WIN54954
(Catalog# : 20280)
WIN54954 is a broad-spectrum antipicornavirus drug.
1214265-56-1 | WZ-3146
(Catalog# : 19191)
WZ-3146 is a covalent or irreversible pyrimidine-based EGFR inhibitor against EGFR T7
1350752-07-6 | 5WKS
(Catalog# : 1812252)
5WKS, also known as ZINC97756584, is a biochemical.
1206731-57-8 | WT161
(Catalog# : 184315)
WT161 is a novel potent, selective, and bioavailable HDAC6 inhibitor.
1431866-33-9 | WEHI-539
(Catalog# : 17101613)
WEHI-539 is a highly potent and selective BCL-XL inhibitor. The pro-survival BCL-2 fa
1354825-58-3 | WEHI-345
(Catalog# : 1781007)
WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events
1214265-58-3 | WZ4003
(Catalog# : 17030203)
WZ4003 is a selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases
1243243-89-1 | Wnt-C59
(Catalog# : 16122846)
Wnt-C59 is a potent porcupine (PORCN) inhibitor. Wnt-C59 inhibits PORCN activity in v
1421227-52-2 | WS3
(Catalog# : 16122747)
WS3 is a cell proliferation inducer via modulation of Erb3 binding protein-1 (EBP1)
153437-55-9 | WHI-P180 hydrochloride
(Catalog# : 611927)
WHI-P180 hydrochloride is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0
1062159-35-6 | WAY-600
(Catalog# : 161009014)
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 n
1062161-90-3 | WYE-687
(Catalog# : 1610912)
WYE-687 is a potent and ATP-competitive and selective inhibitor of mTOR with IC50 of
1144068-46-1 | WYE-125132
(Catalog# : 161009008)
WYE-132 inhibited mTORC1 and mTORC2 in diverse cancer models in vitro and in vivo. Im
1062169-56-5 | WYE-354
(Catalog# : 1610101)
WYE-354 is a potent cell-permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks sig
19545-26-7 | Wortmannin
(Catalog# : 160926005)
It has an in vitro inhibitory concentration (IC50) of around 5 nM, making it a more p
1213269-23-8 | WZ4002
(Catalog# : 52822)
WZ4002 is a novel, mutant-selective EGFR inhibitor for EGFR(L858R)/(T790M) with IC50
1123231-07-1 | WAY-262611
(Catalog# : 52726)
WAY-262611 is a wingless -Catenin agonist that increases bone formation rate; with EC
1421227-53-3 | WS6
(Catalog# : 52224)
WS6 is a novel small molecule that promotes cell proliferation in rodent and human p
152854-19-8 (tartrate) | Xanomeline tartrate
(Catalog# : 2112067)
Xanomeline (LY-246,708) is an orthosteric muscarinic acetylcholine receptor (mAChR) a
1208229-58-6 | XP-23829
(Catalog# : 192143)
XP-23829, also known as tepilamide fumarate, is a hydroxycarboxylic acid receptor 2 l
192939-46-1 | Ximelagatran
(Catalog# : 185282)
Ximelagatran is an anticoagulant that has been investigated extensively as a replacem
1234480-50-2 | XMD8-92
(Catalog# : 17030608)
XMD8-92 is a BMK1 inhibitor and a highly selective inhibitor of ERK5 activity. XMD8-9
1345098-78-3 | XMD16-5
(Catalog# : 17021312)
XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 n
1234480-46-6 | XMD8-87
(Catalog# : 17021311)
XMD8-87 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 38 n
1251156-08-7 | XL388
(Catalog# : 161009016)
XL388 inhibited cellular phosphorylation of mTOR complex 1 (p-p70S6K, pS6, and p-4E-B
1435488-37-1 | XMD17-109
(Catalog# : 16071410)
XMD17-109 is a novel, specific inhibitor of ERK-5 with an EC50 value of 4.2 M in HEK2
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
2891709-58-1 | INDEX NAME NOT YET ASSIGNED
(Catalog# : 25002)
2247396-91-2 | HC-5404
(Catalog# : 25001)
HC-5404 is a novel, highly selective and potent PERK inhibitor.
3034479-99-4 | HC-5404-FU
(Catalog# : 24112)
HC-5404-FU is a novel, highly selective and potent PERK inhibitor.
2309409-79-6 | CMP-5 2HCl
(Catalog# : 24161)
CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activit
2630378-05-9 | Wu-5
(Catalog# : 24160)
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD de
890764-36-0 | VU-29
(Catalog# : 24159)
VU 29 is a potent allosteric potentiator at the rat mGlu5 receptor (EC50 = 9 nM); bin
1221186-52-2 | ML-202
(Catalog# : 24158)
ML-202 is an activator of pyruvate kinase M2 (PKM2).
921193-28-4 | BTA-EG4 hydrate
(Catalog# : 24157)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
2415281-52-4 | CYD19
(Catalog# : 24156)
CYD19 is a potent Snail/HDAC dual target inhibitor.