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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
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PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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Pyrimidines
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On Sale
Intermediates
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Ordering
Contact Us
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
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Services
Custom Synthesis
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Name Index Y
YK-029A
(Catalog# : 20670, Cas# :
2064269-82-3
)
YW2065
(Catalog# : 20494, Cas# :
2131223-85-1
)
YW2065 has excellent anti-colorectal cancer effects in vitro and in vivo. YW2065 achi
YKL-05-099
(Catalog# : 21241, Cas# :
1936529-65-5
)
YKL-05-099 is a selective inhibitor of Salt-Inducible Kinase (SIK).
YCN47284
(Catalog# : 2073105, Cas# :
181147-28-4
)
YCN47284 is an aromatic guanylhydrazone compounds with antimalarial activity.
YUN27078
(Catalog# : 2071610, Cas# :
879127-07-8
)
YUN27078, also known as EGFR inhibitor, is an EGFR inhibitor. It directly depolymeriz
Y06137
(Catalog# : 193193, Cas# :
2226534-49-0
)
Y06137 is a potent and selective BET inhibitor, which binds to the BRD4(1) bromodomai
YF-2 hydrochloride
(Catalog# : 193151, Cas# :
1312005-62-1
)
YF-2 hydrochloride is a highly selective, blood-brain-barrier permeable histone acety
YH239-EE
(Catalog# : 192213, Cas# :
1364488-67-4
)
YH239-EE is a highly potent p53-MDM2 antagonist.
Y-39983 free base
(Catalog# : 185172, Cas# :
199433-58-4
)
Y-39983 (free base), also known as Y-33075, is a potent and selective inhibitor of RO
YL-0919
(Catalog# : 18578, Cas# :
1339058-04-6
)
YL-0919 is a novel 5-HT1A receptor agonist and selective serotonin reuptake inhibitor.
YU-238259
(Catalog# : 1710139, Cas# :
1943733-16-1
)
YU238259 exhibits potent synthetic lethality in the setting of DNA damage response an
Y-29794 Tosylate
(Catalog# : 1791521, Cas# :
143984-17-2
)
Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopept
Y15 hydrochloride
(Catalog# : 17030112, Cas# :
4506-66-5
)
Y15 hydrochloride, also known as FAK Inhibitor 14, is a direct FAK autophosphorylatio
Y-39983 HCl
(Catalog# : 17021305, Cas# :
173897-44-4
)
Y-39983 is a selective rho-associated protein kinase(ROCK) inhibitor with an IC50 o
740 Y-P (PDGFR 740Y-P)
(Catalog# : 17021302, Cas# :
1236188-16-1
)
740 Y-P is cell-permeable phosphopeptide activator ofPI3K. The PDGFR 740Y-P peptide s
YM-58483 (BTP2)
(Catalog# : 17109009, Cas# :
223499-30-7
)
YM-58483/BTP2 is a blocker of store-operated Ca2+ entry (SOCE), which regulates the a
YM-90709
(Catalog# : 16122849, Cas# :
163769-88-8
)
YM-90709 is an interleukin-5 receptor antagonist. YM-90709 inhibits the binding of IL
Y-29794 Tosylate
(Catalog# : 16122848, Cas# :
129184-48-1
)
Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopept
YHO-13351
(Catalog# : 6111512, Cas# :
1346753-00-1
)
YHO-13351 is the water-soluble prodrug of YHO-13177, which is a potent and specific i
YHO-13177
(Catalog# : 6111511, Cas# :
912287-56-0
)
YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of
YM-155 hydrochloride
(Catalog# : 6111414, Cas# :
355406-09-6
)
YM155 is a potent survivin suppressant by inhibiting Survivin promoter activity with
YLF-466D
(Catalog# : 611813, Cas# :
1273323-67-3
)
YLF-466D is an allosteric AMPK activator.YLF466D activated recombinant human 111, 211
Y27632(free base)
(Catalog# : 16070918, Cas# :
146986-50-7
)
Y27632 is a selective ROCK inhibitor, which inhibits ET-1-induced increases in natriu
YK11
(Catalog# : 030910, Cas# :
1370003-76-1
)
Coming soon!
Y-27632 dihydrochloride
(Catalog# : 010421, Cas# :
129830-38-2
)
Y-27632 2Hcl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM, exhibits &g
YM-201636
(Catalog# : 121426, Cas# :
371942-69-7
)
YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110.
YL-109
(Catalog# : 110219, Cas# :
36341-25-0
)
YL-109 has ability to inhibit breast cancer cell growth and invasiveness in vitro and
Y-320
(Catalog# : 52516, Cas# :
288250-47-5
)
Y-320 is a new phenylpyrazoleanilide immunomodulator; inhibits IL-17 production by CD
Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag