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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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Membrane Transporter/Ion Channel
others
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Boronic Acids
Bromides
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Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
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Phenols
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
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Name Index G
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Name Index G
GSK1059865
(Catalog# : 24131, Cas# :
1191044-58-2
)
GSK1059865 is a potent orexin 1 receptor antagonist.
G-5758
(Catalog# : 24076, Cas# :
2413455-99-7
)
GW-280264 ( GW-280264X )
(Catalog# : 24031, Cas# :
866924-39-2
)
GW-280264 ( GW-280264X ) is the mixedADAM10/TACE (ADAM17) metalloproteinasesinhibitor.
Golidocitinib ( AZD-4205 )
(Catalog# : 24028, Cas# :
2091134-68-6
)
Golidocitinib (AZD-4205) is an oral JAK1 selective kinase inhibitor.
Glecirasib
(Catalog# : 20672, Cas# :
2657613-87-9
)
Ganaxolone
(Catalog# : 20630, Cas# :
38398-32-2
)
Ganaxolone, also known as CCD 1042 and C1042, is a CNS-selective GABAA modulator that
GNE-7883
(Catalog# : 20589, Cas# :
2648450-42-2
)
GNE-7883 is a pan-TEAD inhibitor.
GLPG3667
(Catalog# : 20509, Cas# :
2308520-97-8
)
GLPG3667 is an oral potent and selective small-molecule TYK2 inhibitor in development
Glycerol phenylbutyrate ( HPN-100 )
(Catalog# : 230401, Cas# :
611168-24-2
)
Glycerol phenylbutyrate, also known as HPN-100, is under trials in the treatment of c
GSK 525762A
(Catalog# : 171459, Cas# :
1260907-17-2
)
GSK5182
(Catalog# : 20375, Cas# :
877387-37-6 (free base)
)
GSK5182 is a specific inverse agonist for estrogen-related receptor γ.
GF-109203X
(Catalog# : L20356, Cas# :
133052-90-1
)
GF-109203X is a potent and highly selective PCK inhibitor, which inhibits PKC isozyme
GDC-046
(Catalog# : L20342, Cas# :
1258292-64-6
)
GDC-046 is a potent, selective, and orally bioavailable TYK2 inhibitor for TYK2, JAK1
GDC-0214
(Catalog# : c20341, Cas# :
1831144-46-7
)
iJak-381 is a highly potent, selective, and inhalable Janus kinase-1 (JAK-1) inhibito
GYY4137
(Catalog# : L20339, Cas# :
106740-09-4
)
GYY4137 is a novel water-soluble and slow releasing H2S donor. Hydrogen sulfide (H2S)
GDC-0077
(Catalog# : L20335, Cas# :
2060571-02-8
)
Inavolisib, also known as GDC-0077, is a potent and selective PI3K inhibitor. GDC-007
Gloxazone
(Catalog# : 20304, Cas# :
2507-91-7
)
Gloxazone is an effective but toxic anaplasmacide.
Glymidine sodium
(Catalog# : 20295, Cas# :
3459-20-9
)
Glymidine sodium is a sulfonamide hypoglycemic agent which stimulates insulin secreti
Golgicide A
(Catalog# : 20292, Cas# :
1139889-93-2
)
Golgicide A is a Potent, selective and reversible inhibitor of GBF1 ArfGEF. Golgicide
GDC-0077
(Catalog# : 20283)
GDC-0077 is a potent and selective PI3K inhibitor. GDC-0077 blocks an enzyme involved
GS 0573 ( PMEDAP )
(Catalog# : 20275, Cas# :
113852-41-8
)
GS 0573 is an antiviral compound that has been studied for potential treatment of Fel
Giredestrant tartrate
(Catalog# : 20263, Cas# :
2407529-33-1
)
Giredestrant tartrate (GDC-9545 tartrate), a non-steroidal ER ligand, is an orally ac
Giredestrant
(Catalog# : 21248, Cas# :
1953133-47-5
)
Giredestrant, also known as GDC-9545 and RG6171, is a SERD. GDC-9545 is an orally ava
GNF-PF-3777
(Catalog# : 21226, Cas# :
77603-42-0
)
GNF-PF-3777 is a derivative of tryptanthrin.
GSK484 HCl
(Catalog# : 20111801, Cas# :
1652591-81-5
)
GSK484 is a potent PAD-4 inhibitor (Protein-arginine deiminase type-4). GSK484 potent
GCN2iB
(Catalog# : 2071802, Cas# :
2183470-12-2
)
GCN2iB is an ATP-competitive GCN2 inhibitory compound with a better pharmacokinetic p
GRL0617
(Catalog# : 2071625, Cas# :
1093070-16-6
)
GRL0617 is a potent, selective and competitive noncovalent inhibitor of SARS PLPro. G
GS-441524
(Catalog# : 2071546, Cas# :
1191237-69-0
)
GS-441524 is a potent inhibitor of feline infectious peritonitis (FIP) virus with an
GSK3145095
(Catalog# : 2071533, Cas# :
1622849-43-7
)
GSK3145095 is a potent and orally active RIPK1 inhibitor (IC50 = 5 nM) with potential
GSK2894631A
(Catalog# : 2071528, Cas# :
2101626-26-8
)
GSK2894631A is a hematopoietic PGD synthase (HPGDS) inhibitor.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Reparixin
(Catalog# : 25050, Cas# :
266359-83-5
)
Reparixin is an inhibitor of CXCR2 function, which attenuates inflammatory responses
TAK-779
(Catalog# : 25049, Cas# :
229005-80-5
)
TAK-779 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist potentially for
BAY-1125976
(Catalog# : 25048, Cas# :
1402608-02-9
)
BAY-1125976 is a potent and selective allosteric AKT1/2 inhibitor. BAY-1125976 exhibi
Vimseltinib free base
(Catalog# : 25047, Cas# :
1628606-05-2
)
Vimseltinib, also known as DCC-3014, is a potent and orally active inhibitor of the t
2-Propynamide, 3-[(3Z)-3-[[[4-[(dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indol-6-yl]-N-ethyl-
(Catalog# : 25046, Cas# :
2128698-24-6
)
Cavosonstat
(Catalog# : 25045, Cas# :
1371587-51-7
)
Cavosonstat, alos known as N91115) an orally bioavailable inhibitor of S-nitrosogluta
Ivospemin Hydrochloride
(Catalog# : 25044, Cas# :
259657-09-5
)
Ivospemin is an antineoplastic spermine analogue.
Survodutide
(Catalog# : 25043, Cas# :
2805997-46-8
)
XRD-0394
(Catalog# : 25042, Cas# :
2595308-10-2
)
XRD-0394 is a DNA-PKcs inhibitor. XRD-0394 selectively targets, binds to and inhibits
CC-90003
(Catalog# : 25041, Cas# :
1621999-82-3
)
CC-90003 is an orally available inhibitor of extracellular signal-regulated kinase (E