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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
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others
PROTAC
Building Blocks
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Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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Pyridines
Pyrimidines
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Ordering
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
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On Sale
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Name Index G
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Name Index G
GSK-2830371
(Catalog# : 1810292, Cas# :
1404456-53-6
)
GSK 2830371 is a WiP1 inhibitor. It inhibits cell growth and tumor growth in lymphoma
GENZ-882706
(Catalog# : 1810176, Cas# :
2070864-35-4
)
GENZ-882706 is a potent colony stimulating factor-1 receptor (CSF-1R) Inhibitor.
GDC-0575
(Catalog# : 189272, Cas# :
1196541-47-5
)
GDC-0575 (ARRY-575, RG7741) is a potent and selective CHK1 inhibitor with an IC50 of
GSK-626616
(Catalog# : 188241, Cas# :
1025821-33-3
)
GSK 626616 is a YAK3/DYRK3 kinase inhibitor. It is a chemoprotective agent for the po
GT 949
(Catalog# : 187182, Cas# :
460330-27-2
)
GT 949 is a selective EAAT2 positive allosteric modulator (EC50 = 0.26 nM). Enhances
GSK-J4 free base
(Catalog# : 187163, Cas# :
1373423-53-0
)
GSK-J4 is a cell permeable, potent and selective histone demethylase.
Gefapixant
(Catalog# : 187122, Cas# :
1015787-98-0
)
Gefapixant, also known as AF-219 or MK-7264, is a P2X3 receptor antagonist. Gefapixan
GLL398
(Catalog# : 185313, Cas# :
2077980-83-5
)
GLL398 is an Oral Selective Estrogen Receptor Downregulator.
Glecaprevir
(Catalog# : 185311, Cas# :
1365970-03-1
)
Glecaprevir, also known as ABT-493 and A-1282576, is a NS 3/4A inhibitor potentially
GW843682X
(Catalog# : 185292, Cas# :
660868-91-7
)
GW843682X is a selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase
GNE-7915
(Catalog# : 18595, Cas# :
1351761-44-8
)
GNE-7915 is a potent LRRK2 kinase inhibitor.
GLPG1837
(Catalog# : 1842811, Cas# :
1654725-02-6
)
GLPG-1837, also known as ABBV-974, is a novel cystic fibrosis transmembrane conductan
GC376 sodium
(Catalog# : 184175, Cas# :
1416992-39-6
)
GC376 is a 3CLpro inhibitor (3C-like protease inhibitor).
GNF-6231
(Catalog# : 18494, Cas# :
1243245-18-2
)
GNF-6231 is a potent, selective, and orally bioavailable Porcupine inhibitor that blo
GSK-3326595
(Catalog# : 184316, Cas# :
1616392-22-3
)
GSK-3326595, also known as EPZ015938, is an orally active, potent and selective inhib
GIBH-130
(Catalog# : 18428, Cas# :
1252608-59-5
)
GIBH-130是一种神经炎症抑制剂。
GSK872
(Catalog# : 17101621, Cas# :
1346546-69-7
)
GSK872 is a a receptor interacting protein kinase-3 (RIP3) inhibitor. GSK872 inhibits
GSK2881078
(Catalog# : 1791316, Cas# :
1539314-06-1
)
GSK-2881078 is a selective androgen receptor modulator potentially for the treatment
GJ-103 sodium
(Catalog# : 1791116, Cas# :
1459687-96-7
)
GJ103 sodium salt is an active analog of the read-through compound GJ072.
GJ-103 free acid
(Catalog# : 1791115, Cas# :
1459687-89-8
)
GJ-103 is an active analog of the read-through compound GJ072. Chemical-induced read
10074-G5
(Catalog# : 1791112, Cas# :
413611-93-5
)
10074-G5 is a c-Myc/Max interaction inhibitor. 10074-G5, similarly to 10058-F4 (#F368
GW0742
(Catalog# : 1791110, Cas# :
317318-84-6
)
GW0742, also known as GW610742 and GW0742X is a PPARδ/β agonist. GW0742 Induces Ear
Givinostat HCl
(Catalog# : 17919, Cas# :
199657-29-9
)
Givinostat or gavinostat, aslo known as ITF2357, is a potent and orally active histon
Grazoprevir hydrate
(Catalog# : 1783018, Cas# :
1350462-55-3
)
Grazoprevir, also known as MK5172, is a drug approved for the treatment of hepatitis
GNE-3511
(Catalog# : 1781006, Cas# :
1496581-76-0
)
GNE-3511 is a potent and selective dual leucine zipper kinase (DLK, MAP3K12) inhibito
GSK2193874
(Catalog# : 178914, Cas# :
1336960-13-4
)
GSK2193874 was identified as a selective, orally active TRPV4 blocker that inhibits C
GW4869
(Catalog# : 178912, Cas# :
6823-69-4
)
GW4869 (dihydrochloride hydrate) is a cell permeable, selective inhibitor of N-SMase
GSK2982772
(Catalog# : 178911, Cas# :
1622848-92-3
)
GSK2982772 is an ATP competitive eceptor-interacting protein-1 (RIP1) kinase inhibit
GSK180736A (GSK180736)
(Catalog# : 178901, Cas# :
817194-38-0
)
GSK180736A is potent and selective inhibitor of GRK2 with an IC50 of 0.77 M25 and >10
GSK2269557
(Catalog# : 2017883, Cas# :
1254036-77-5
)
GSK2269557,also known as GSK-2269557, is a potent and selective PI3K inhibitor.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag