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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
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PROTAC
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Bromides
Carboxes
Catalysts
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Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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Pyridines
Pyrimidines
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
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Name Index G
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Name Index G
GSK-1070916
(Catalog# : 111011, Cas# :
942918-07-2
)
GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3
GSK269962A
(Catalog# : 102206, Cas# :
850664-21-0
)
GSK269962A(CAS 850664-21-0) is a potent ROCK inhibitor (IC50 values are 1.6 and 4 nM
Gandotinib(LY2784544)
(Catalog# : 91415, Cas# :
1229236-86-5
)
Gandotinib is an orally bioavailable imidazopyridazine and inhibitor of Janus kinase
GW 627368
(Catalog# : 91003, Cas# :
439288-66-1
)
GW 627368X is a potent and selective competitive antagonist of the EP4 receptor with
GDC-0810 ( Brilanestrant , ARN-810 )
(Catalog# : 90731, Cas# :
1365888-06-7
)
GDC-0810 (Brilanestrant, ARN-810, RG6046) is a selective estrogen receptor degrader (
G007-LK
(Catalog# : 62908, Cas# :
1380672-07-0
)
G007-LK is specific tankyrase 1/2 inhibitor.G007-LK (66) displayed high selectivity t
GDC-0349
(Catalog# : 62702, Cas# :
1207360-89-1
)
GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR.
Galeterone
(Catalog# : 62003, Cas# :
851983-85-2
)
Galeterone(VN/124-1,TOK001) is a highly selective, multi-targeted, oral small molecul
Gimeracil
(Catalog# : 52804, Cas# :
103766-25-2
)
Gimeracil(Gimestat) is an inhibitor of dihydropyrimidine dehydrogenase (DPYD), which
GSK 525762A
(Catalog# : 52745, Cas# :
1260907-17-2
)
GSK 525762A (I-BET 762) is an inhibitor for BET proteins with IC50 of ~35 nM.
GSK429286A
(Catalog# : 52629, Cas# :
864082-47-3
)
GSK429286A is a selective inhibitor of ROCK1 and ROCK2 with IC50 of 14 nM and 63 nM,
GSK1059615
(Catalog# : 52628, Cas# :
958852-01-2
)
GSK1059615 is a dual inhibitor of PI3K/// (reversible) and mTOR with IC50 of 0.4 nM/0
GKT137831
(Catalog# : 52627, Cas# :
1218942-37-0
)
GKT137831 is a novel and specific dual Nox1/Nox4 inhibitor with Ki of 14040 nM and 11
GSK2636771
(Catalog# : 52618, Cas# :
1372540-25-4
)
GSK2636771 is a potent, orally bioavailable and selective inhibitor of PI3K (0.89 nM)
GS-7340
(Catalog# : 52611, Cas# :
379270-37-8
)
GS-7340(Tenofovir alafenamide) is a prodrug of tenofovir (TFV) that more efficiently
GSK2110183
(Catalog# : 52584, Cas# :
1047634-63-8
)
GSK2110183 is an orally bioavailable, selective, ATP-competitive and potent pan-Akt i
GW788388
(Catalog# : 52305, Cas# :
452342-67-5
)
GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, also inhibit
GNF-5
(Catalog# : 52216, Cas# :
778277-15-9
)
GNF-5, an analogue of GNF-2 with improved pharmacokinetic properties, is a selective
GNF-2
(Catalog# : 52301, Cas# :
778270-11-4
)
GNF-2 is a highly selective non-ATP competitive inhibitor of oncogenic Bcr-Abl activi
GS967
(Catalog# : 52216, Cas# :
1262618-39-2
)
GS967 is a novel, potent, and selective inhibitor of cardiac late sodium current(late
GBR 12935 dihydrochloride
(Catalog# : 52404, Cas# :
67469-81-2
)
GBR 12935 2Hcl is a potent, and selective dopamine reuptake inhibitor.
GSK126
(Catalog# : 52208, Cas# :
1346574-57-9
)
GSK126 is a potent, highly selectiveEZH2 methyltransferaseinhibitor withIC50of 9.9 nM
GSK503
(Catalog# : 51805, Cas# :
1346572-63-1
)
GSK-503 is a potent EZH2 inhibitor with potential anticancer activity. Reference: 1.
GW9662
(Catalog# : 52304, Cas# :
22978-25-2
)
GW9662 is a selective PPAR antagonist forPPARwithIC50of 3.3 nM, with at least 100 to
GNE-317
(Catalog# : 52215, Cas# :
1394076-92-6
)
GNE-317 is a potent, brain-penetrantPI3Kinhibitor
Genz-123346
(Catalog# : S1419, Cas# :
491833-30-8
)
Genz-123346 free base is an inhibitor of GL1 synthase that blocks the conversion of c
Galunisertib(LY2157299)
(Catalog# : 52017, Cas# :
700874-72-2
)
Galunisertib (LY2157299)isselective TGF- receptor kinase inhibitor. Galunisertib was
GSK3787
(Catalog# : 52018, Cas# :
188591-46-0
)
GSK3787 is as a selective and irreversible antagonist ofPPARwithpIC50of 6.6, with no
GSK 2656157
(Catalog# : 52019, Cas# :
1337532-29-2
)
GSK2656157 is an ATP-competitive and highly selective inhibitor ofPERKwithIC50of 0.9
Golvatinib (E7050)
(Catalog# : 52020, Cas# :
928037-13-2
)
Golvatinib (E7050) is a dualc-MetandVEGFR-2inhibitor with IC50 of 14 nM and 16 nM, do
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag