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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
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Angiogenesis
Apoptosis
Autophagy
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MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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Cas Index 9
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Cas Index 9
919783-22-5 | AZD-1656
(Catalog# : 24070)
AZD-1656 is a glucokinase (GK) activator potentially for the treatment of type 2 diab
951884-75-6 | 2-Amino-5-bromo-4-methoxy-3-pyridinecarbonitrile
(Catalog# : 20424)
952753-59-2 | 2-amino-4-(4-fluorophenyl)thiazole-5-carbonitrile
(Catalog# : 20400)
958295-17-5 | AGN 196996
(Catalog# : 226191)
AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little b
96566-25-5 (free acid) | Ablukast
(Catalog# : 20319)
Ablukast is a leuktriene receptor antagonist that acts as an anti-asthmatic.
959850-74-9 | AP1189 acetate
(Catalog# : 2105071)
AP1189 is a melanocortin receptor agonist on MC1 and MC3 receptors.
932372-01-5 | Asapiprant
(Catalog# : 2051515)
Asapiprant is a potent and selective DP1 receptor antagonist, with a Ki of 0.44 nM. A
942507-42-8 | AZ304
(Catalog# : 19363)
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits wild type B
913548-29-5 | AR-9281
(Catalog# : 191146)
AR-9281 is a soluble epoxide hydrolase (s-EH) inhibitor potentially for the treatment
949164-09-4 | ALX 1393
(Catalog# : 185213)
ALX 1393 is a glycine transporter-2 inhibitor.
919486-40-1 | AS-1517499
(Catalog# : 185187)
AS-1517499 is a potent and selective STAT6 inhibitor.
943764-99-6 | Acebilustat
(Catalog# : 179159)
Acebilustat, also known as ZK322, is a potent and selective leukotriene A4 hydrolase
924641-59-8 | AZD-5597
(Catalog# : 16122865)
AZD-5597 is potent CDK inhibitor with in vitro anti-proliferative effects against a r
942398-84-7 | Amiselimod HCl
(Catalog# : 16122856)
Amiselimod, also known as MT1303, is a potent and selective immunosuppressant and sph
9087-70-1 | Aprotinin
(Catalog# : 16122761)
Aprotinin is a small protein serine protease inhibitor, used to reduce perioperative
959746-77-1 | A-836339
(Catalog# : 6111107)
A-836339 is a cannabinoid CB2 receptor-selective agonist; exhibits high potencies at
900515-16-4 | AS-252424
(Catalog# : 160926012)
AS-252424 is a potent and selective small-molecule PI3Kgamma inhibitor. Oral administ
937265-83-3 | Arry-380
(Catalog# : 021801)
ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent again
918407-35-9 | Avoralstat
(Catalog# : 011813)
Avoralstat (formerly BCX4161) is a potent small-molecule oral plasma kallikrein inhib
945595-80-2 | AMG 900
(Catalog# : 011803)
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/
916170-19-9 | AC-55541
(Catalog# : 011302)
AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist.
935666-88-9 | AZD-1480
(Catalog# : 010816)
AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM, selectivity a
935881-37-1 | AR-42
(Catalog# : 123009)
AR-42 is a novel, oral cancer therapy currently in early clinical development.
934162-61-5 | A-966492
(Catalog# : 123006)
A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with Ki of 1 nM and 1.5 n
90779-69-4 | Atosiban acetate
(Catalog# : 122931)
Atosiban is a nonapeptide, desamino-oxytocin analogue, and a competitive vasopressin/
909910-43-6 | A 83-01
(Catalog# : 122843)
A 83-01 is a selective inhibitor of TGF- type I receptor ALK5 kinase, type I activin/
924416-43-3 | AdipoRon
(Catalog# : 122822)
AdipoRon is a novel small-molecule AdipoR agonist; binds to both AdipoR1(Kd= 1.8 uM)
90141-22-3 | AT-101
(Catalog# : 121434)
AT-101 is the orally bioavailable the R-(-) enantiomer of gossypol with potential ant
939805-30-8 | ACTB-1003
(Catalog# : 102619)
ACTB-1003 is a potent inhibitor of FGFR1 with IC50 <10 nM in FGFR-1 biochemical as
902135-91-5 | AT7519 Hydrochloride
(Catalog# : 82702)
AT7519 hydrochloride is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
921193-28-4 | BTA-EG4 hydrate
(Catalog# : 24157)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
2415281-52-4 | CYD19
(Catalog# : 24156)
CYD19 is a potent Snail/HDAC dual target inhibitor.
98570-83-3 | Phylloflavan
(Catalog# : 24155)
Phylloflavan is an antileishmanial agent with an intracellular EC50 of 3.2 nM in RAW
312611-92-0 | VK-28
(Catalog# : 24154)
VK-28, a brain-permeable iron chelator, inhibits both basal and Fe/ascorbate-induced
160162-42-5 | SR-11302
(Catalog# : 24153)
SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor.
2171065-77-1 | AKOS037652256
(Catalog# : 24152)
AKOS037652256 can be used as a TRPML modulator for the treatment of diseases associat
2990506-75-5 | ML353
(Catalog# : 24151)
ML353 is a selective ligand of mGlu5 silent allosteric modulator (SAM).
1208448-95-6 | MIF098
(Catalog# : 24150)
MIF098 is a macrophage migration inhibitory factor (MIF) antagonist.
2319722-53-5 | TM5441sodium
(Catalog# : 24149)
TM-5441, also known as EBP 883 and BMS-790052, is a potent plasminogen activator inhi
2794934-49-7 | RGT-018
(Catalog# : 24148)
RGT-018 is a potent and orally active SOS1 inhibitor with anti-tumor effects.