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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Cas Index 1
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Cas Index 1
1624117-53-8 | XY1
(Catalog# : 021803)
XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhi
1365267-27-1 | X-396
(Catalog# : 011804)
X-396 is an orally available small molecule inhibitor of the receptor tyrosine kinase
1123889-87-1 | XL765
(Catalog# : 111910)
XL765 is a PI3K/mTOR dual kinase inhibitor with IC50 values of 157 nM, 39 nM, 113 nM,
1515856-92-4 | XEN445
(Catalog# : 52501)
XEN445 is a potent and selective EL inhibitor(IC50=0.237 uM), that showed good ADME a
1936529-65-5 | YKL-05-099
(Catalog# : 21241)
YKL-05-099 is a selective inhibitor of Salt-Inducible Kinase (SIK).
181147-28-4 | YCN47284
(Catalog# : 2073105)
YCN47284 is an aromatic guanylhydrazone compounds with antimalarial activity.
1312005-62-1 | YF-2 hydrochloride
(Catalog# : 193151)
YF-2 hydrochloride is a highly selective, blood-brain-barrier permeable histone acety
1364488-67-4 | YH239-EE
(Catalog# : 192213)
YH239-EE is a highly potent p53-MDM2 antagonist.
199433-58-4 | Y-39983 free base
(Catalog# : 185172)
Y-39983 (free base), also known as Y-33075, is a potent and selective inhibitor of RO
1339058-04-6 | YL-0919
(Catalog# : 18578)
YL-0919 is a novel 5-HT1A receptor agonist and selective serotonin reuptake inhibitor.
1943733-16-1 | YU-238259
(Catalog# : 1710139)
YU238259 exhibits potent synthetic lethality in the setting of DNA damage response an
143984-17-2 | Y-29794 Tosylate
(Catalog# : 1791521)
Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopept
173897-44-4 | Y-39983 HCl
(Catalog# : 17021305)
Y-39983 is a selective rho-associated protein kinase(ROCK) inhibitor with an IC50 o
1236188-16-1 | 740 Y-P (PDGFR 740Y-P)
(Catalog# : 17021302)
740 Y-P is cell-permeable phosphopeptide activator ofPI3K. The PDGFR 740Y-P peptide s
163769-88-8 | YM-90709
(Catalog# : 16122849)
YM-90709 is an interleukin-5 receptor antagonist. YM-90709 inhibits the binding of IL
129184-48-1 | Y-29794 Tosylate
(Catalog# : 16122848)
Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopept
1346753-00-1 | YHO-13351
(Catalog# : 6111512)
YHO-13351 is the water-soluble prodrug of YHO-13177, which is a potent and specific i
1273323-67-3 | YLF-466D
(Catalog# : 611813)
YLF-466D is an allosteric AMPK activator.YLF466D activated recombinant human 111, 211
146986-50-7 | Y27632(free base)
(Catalog# : 16070918)
Y27632 is a selective ROCK inhibitor, which inhibits ET-1-induced increases in natriu
1370003-76-1 | YK11
(Catalog# : 030910)
Coming soon!
129830-38-2 | Y-27632 dihydrochloride
(Catalog# : 010421)
Y-27632 2Hcl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM, exhibits &g
1632051-40-1 | Zuranolone
(Catalog# : 24105)
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
1606974-33-7 | Zatolmilast
(Catalog# : 20651)
Zatolmilast is a phosphodiesterase IV inhibitor.
1851412-93-5 | Zavondemstat
(Catalog# : 20610)
Zavondemstat is a KDM4 inhibitor with potential as an antineoplastic agent.
1438280-73-9 | 1Z105
(Catalog# : 20567)
1Z105 is a TLR4/MD2 ligand, significantly reducing the IL-6 secretion by subsequent c
1211825-25-0 | ZINC40099027 (ZN27)
(Catalog# : 20513)
ZINC40099027 (ZN27) is a specific focal adhesion kinase (FAK) activator that promotes
1661854-97-2 | Zipalertinib
(Catalog# : 20317)
Zipalertinib, also known as TAS6417, CLN-081, is a Novel EGFR Inhibitor Targeting Exo
1713240-67-5 | Zegocractin ( CM-4620 )
(Catalog# : 204504)
Zegocractin (CM-4620, Auxora(TM)) is a small-molecule inhibitor of the calcium releas
1199236-64-0 | Z944
(Catalog# : 181233)
Z944 is a T-type calcium channel antagonist potentially for the treatment of pain. Z9
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
2891709-58-1 | INDEX NAME NOT YET ASSIGNED
(Catalog# : 25002)
2247396-91-2 | HC-5404
(Catalog# : 25001)
HC-5404 is a novel, highly selective and potent PERK inhibitor.
3034479-99-4 | HC-5404-FU
(Catalog# : 24112)
HC-5404-FU is a novel, highly selective and potent PERK inhibitor.
2309409-79-6 | CMP-5 2HCl
(Catalog# : 24161)
CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activit
2630378-05-9 | Wu-5
(Catalog# : 24160)
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD de
890764-36-0 | VU-29
(Catalog# : 24159)
VU 29 is a potent allosteric potentiator at the rat mGlu5 receptor (EC50 = 9 nM); bin
1221186-52-2 | ML-202
(Catalog# : 24158)
ML-202 is an activator of pyruvate kinase M2 (PKM2).
921193-28-4 | BTA-EG4 hydrate
(Catalog# : 24157)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
2415281-52-4 | CYD19
(Catalog# : 24156)
CYD19 is a potent Snail/HDAC dual target inhibitor.