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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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Cas号索引 9
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Cas号索引 9
938435-69-9 | Flobetair
(Catalog# : 102904)
Coming soon!
939055-18-2 | FIPI
(Catalog# : 102617)
FIPI is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) a
942206-85-1 | GSK1016790A
(Catalog# : 2071511)
GSK1016790A, also known as GSK101, is a TRPV4 agonist that elicits calcium influx in
901245-65-6 | GSK-5959
(Catalog# : 1811266)
GSK-5959是一种有效的选择性BRPF1溴域抑制剂(IC50 = 80 nM)。
937174-76-0 | GSK-690693
(Catalog# : 161009019)
Pan-AKT kinase inhibitor GSK-690693 binds to and inhibits Akt kinases 1, 2, and 3, wh
929095-18-1 | GSK-461364
(Catalog# : 16071032)
GSK-461364 is a Polo-like kinase 1 inhibitor, is also a small molecule Polo-like kina
936694-12-1 | Glesatinib(MGCD-265)
(Catalog# : 012001)
Glesatinib is a potent tyrosine kinase inhibitor with potential antineoplastic activi
937812-80-1 | Gamma-Secretase Modulators
(Catalog# : 011909)
Coming soon!
957054-30-7 | GDC-0941
(Catalog# : 120115)
GDC-0941 is a potent inhibitor of PI3K/ with IC50 of 3 nM, with modest selectivity ag
942918-07-2 | GSK-1070916
(Catalog# : 111011)
GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3
958852-01-2 | GSK1059615
(Catalog# : 52628)
GSK1059615 is a dual inhibitor of PI3K/// (reversible) and mTOR with IC50 of 0.4 nM/0
928037-13-2 | Golvatinib (E7050)
(Catalog# : 52020)
Golvatinib (E7050) is a dualc-MetandVEGFR-2inhibitor with IC50 of 14 nM and 16 nM, do
924296-39-9 | HBX-41108
(Catalog# : 19317)
HBX 41108是泛素特异性蛋白酶(USP) 7的抑制剂。HBX 41108通过IC(50)在亚
941987-60-6 | H 151
(Catalog# : 1811022)
H 151是一种诱捕拮抗剂,共价结合在Cys91上,阻断棕榈酰化和防止
934343-74-5 | HSP990 (NVP-HSP990)
(Catalog# : 52015)
NVP-HSP990 (HSP990) is a novel, potent and selectiveHSP90inhibitor for HSP90/ withIC5
942123-43-5 | Inarigivir soproxil
(Catalog# : 186277)
Inarigivir soproxil,也被称为SB 9200,是一种抗病毒药物。
901751-47-1 | iCRT3
(Catalog# : 18492)
iCRT3是Wnt/β-catenin信号的拮抗剂,在Wnt responsive STF16-luc reporter assay
945526-43-2 | ISCK03
(Catalog# : 1791118)
ISCK03是一种有效的c-kit抑制剂。ISCK03抑制在501mel人黑素瘤细胞的SC
914638-30-5 | IDO-IN-1
(Catalog# : 16122822)
IDO-IN-1 is a potent and selective indoleamine-2,3-dioxygenase (IDO) inhibitor with I
937263-43-9 | Irbinitinib
(Catalog# : 011310)
Irbinitinib is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent ag
914471-09-3 | IDO-IN-2
(Catalog# : 123002)
IDO-IN-2 is a potent IDO1 inhibitor(IC50=10 nM) with desirable pharmaceutical propert
99059-64-0 | 3-iodo-4-isopropylbenzoic acid
(Catalog# : 80313)
Coming soon!
931398-72-0 | IOX2
(Catalog# : 52527)
IOX2 is a selective inhibitor of the Hypoxia Inducible Factor (HIF) Prolyl-Hydroxylas
943540-74-7 | JNJ-38877618
(Catalog# : 204307)
JNJ-38877618 is a hepatocyte growth factor receptor (HGFR; MET; c-Met) inhibitor pote
900573-88-8 | JI-101
(Catalog# : 16122823)
JI-101 is an orally active inhibitor of vascular endothelial growth factor receptor 2
952849-76-2 | KKL-10
(Catalog# : 184217)
KKL-10是一种抗菌药物。KKL-10在体外和体外感染中均表现出了对弱毒
927822-86-4 | KC7F2
(Catalog# : 16122827)
KC7F2 is a potent HIF-1 pathway inhibitor with potential anticancer activity. KC7F2 i
938440-64-3 | Ku-0063794
(Catalog# : 121424)
KU-0063794 is a selective inhibitor of mammalian target of rapamycin (mTOR) (IC50 ~10
925701-49-1 | KU-60019
(Catalog# : 52576)
KU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM
924835-67-6 | LP-184
(Catalog# : 24121)
LP-184 is an acylfulvene-derived prodrug activated by the oxidoreductase PTGR1 that a
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
667411-04-3 | TRPM4-IN-2
(Catalog# : 24147)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
1534-35-6 | Isolithocholic Acid
(Catalog# : 24146)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
877768-84-8 | H2-Gamendazole
(Catalog# : 24145)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
2095432-28-1 | CPI-455 HCl
(Catalog# : 24144)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
1215115-03-9 | KH-3
(Catalog# : 24143)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
2097938-74-2 | Stafib-2
(Catalog# : 24142)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
2032123-28-5 | TCRS-417
(Catalog# : 24141)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
1096144-06-7 | PST3 1a
(Catalog# : 24140)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
2225824-53-1 | YTX-465
(Catalog# : 24139)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
944808-88-2 | CAY10566
(Catalog# : 10403)
Coming soon!