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抑制剂/受体激动剂
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Epigenetics
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Angiogenesis
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Cytoskeletal Signaling
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Bromides
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Deuterated
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Indoles and Oxindoles
Iodos
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Peg Linkers
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联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 Z
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产品名字索引 Z
ZINC20451377
(Catalog# : 24132, Cas# :
2306303-35-3
)
ZINC20451377 is a small molecule that binds to hepatitis B surface antigen (HBsAg) wi
Z-LEHD-FMK
(Catalog# : 24127, Cas# :
210345-04-3
)
Z-LEHD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-9. Z-LE
Z-IETD-FMK
(Catalog# : 24126, Cas# :
210344-98-2
)
MDK4982, also known as Z-IETD-FMK, is a potent, cell-permeable, irreversible inhibito
Z-DEVD-fmk
(Catalog# : 24125, Cas# :
210344-95-9
)
Z-DEVD-fmk is a cell-permeable, irreversible inhibitor of caspase-3. Caspase-3 is a c
Zastaprazan
(Catalog# : 24123, Cas# :
2133852-18-1
)
Zastaprazan, also known as JP-1366, is a proton pump inhibitor. JP-1366 mediates stro
Zuranolone
(Catalog# : 24105, Cas# :
1632051-40-1
)
Zurletrectinib
(Catalog# : 24104, Cas# :
2403703-30-8
)
Zurletrectinib is a tyrosine kinase inhibitor with potential as an antineoplastic age
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil 是一种有效的、高选择性的口服活性抑制剂,针对 Rho 相关
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib 是一种口服、有效、选择性的小分子抑制剂,针对 menin 和
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib是一种在研口服丝裂原活化蛋白激酶活化蛋白激酶2(MK2
Zongertinib ( BI 1810631 )
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] 是一种人表皮生长因子受体 2 (HER2) 抑制剂。
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib是一种作用于非受体酪氨酸蛋白激酶 (TYK2)靶点的抑制
Zilurgisertib
(Catalog# : 20657, Cas# :
2173389-57-4
)
Zilurgisertib(之前称为 INCB 00928)是一种激活素受体样激酶 2(ALK2,
Zatolmilast
(Catalog# : 20651, Cas# :
1606974-33-7
)
Zatolmilast is a phosphodiesterase IV inhibitor.
Zagociguat
(Catalog# : 20628, Cas# :
2201048-82-8
)
Zagociguat is a guanylate cyclase activator.
Zavondemstat
(Catalog# : 20610, Cas# :
1851412-93-5
)
Zavondemstat 是一种 KDM4 抑制剂,具有抗肿瘤药物的潜力。
1Z105
(Catalog# : 20567, Cas# :
1438280-73-9
)
1Z105 is a TLR4/MD2 ligand, significantly reducing the IL-6 secretion by subsequent c
Zidesamtinib ( NVL-520 )
(Catalog# : 20524, Cas# :
2739829-00-4
)
Zidesamtinib ( NVL-520 ) 是一种新型脑渗透性 ROS1 选择性酪氨酸激酶抑
ZINC40099027 (ZN27)
(Catalog# : 20513, Cas# :
1211825-25-0
)
ZINC40099027 (ZN27) 是一种特异性粘着斑激酶 (FAK) 激活剂,可促进缺血
Zotizalkib ( TPX-0131 )
(Catalog# : 20318, Cas# :
2648641-36-3
)
TPX-0131是下一代 ALK 抑制剂候选药物,目前正在我们针对 ALK+ 晚期
Zipalertinib
(Catalog# : 20317, Cas# :
1661854-97-2
)
Zipalertinib, also known as TAS6417, CLN-081, is a Novel EGFR Inhibitor Targeting Exo
ZZW-115
(Catalog# : 20301, Cas# :
801991-87-7
)
ZZW-115is a potent NUPR1 inhibitor. ZZW-115 induces ferroptosis in a mitochondria-dep
(3Z)-5-bromo-3-[(3-bromo-4,5-dihydroxyphenyl)methylidene]-1H-indol-2-one
(Catalog# : 2071629, Cas# :
486443-73-6
)
LC3-mHTT-IN-AN1 (Compound AN1) is amHTT-LC3linker compound, which interacts with both
ZK824859
(Catalog# : 2071513, Cas# :
2254001-81-3
)
ZK824859 is a potent uPA inhibitor as a potential treatment for multiple sclerosis. Z
Zegocractin ( CM-4620 )
(Catalog# : 204504, Cas# :
1713240-67-5
)
Zegocractin (CM-4620, Auxora(TM)) 是钙释放激活钙通道蛋白 1(CRAC 通道,
ZL0454
(Catalog# : 193281, Cas# :
2229042-77-5
)
ZL0454是一种有效的选择性BRD4抑制剂。ZL0454减少气道炎症,抑制TLR3-
ZM223
(Catalog# : 19352, Cas# :
2031177-48-5
)
ZM223是一种新型非磺胺NEDD8激活酶抑制剂,对HCT116结肠癌细胞具有
Z944
(Catalog# : 181233, Cas# :
1199236-64-0
)
Z944是一种T型钙通道拮抗剂,有望用于疼痛的治疗。Z944对癫痫大鼠
Zamicastat
(Catalog# : 189271, Cas# :
1080028-80-3
)
Zamicastat是一个强有力的和选择性的多巴胺β-mono-oxygenase抑制剂。
扎达维林
(Catalog# : 185186, Cas# :
101975-10-4
)
扎达维林是一种磷酸二酯酶3/4抑制剂。
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
TRPM4-IN-2
(Catalog# : 24147, Cas# :
667411-04-3
)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
Isolithocholic Acid
(Catalog# : 24146, Cas# :
1534-35-6
)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
H2-Gamendazole
(Catalog# : 24145, Cas# :
877768-84-8
)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
CPI-455 HCl
(Catalog# : 24144, Cas# :
2095432-28-1
)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
KH-3
(Catalog# : 24143, Cas# :
1215115-03-9
)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
Stafib-2
(Catalog# : 24142, Cas# :
2097938-74-2
)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
TCRS-417
(Catalog# : 24141, Cas# :
2032123-28-5
)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
PST3 1a
(Catalog# : 24140, Cas# :
1096144-06-7
)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
YTX-465
(Catalog# : 24139, Cas# :
2225824-53-1
)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
CAY10566
(Catalog# : 10403, Cas# :
944808-88-2
)
Coming soon!